Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2493727 | 1.00 | PTGDR2 (0.46) | PTGDR2HDAC1HDAC2TP53MAOB | |
| SCHEMBL1904540 | 0.88 | PTGDR2 (0.49) | PTGDR2 | |
| SCHEMBL1904539 | 0.88 | PTGDR2 (0.49) | PTGDR2 | |
| SCHEMBL1904003 | 0.82 | MTNR1A (0.53) | PTGDR2 | |
| SCHEMBL1904002 | 0.82 | MTNR1A (0.53) | PTGDR2 | |
| SCHEMBL1907504 | 0.81 | PTGDR2 (0.47) | PTGDR2 | |
| SCHEMBL2489729 | 0.81 | PTGDR2 (0.47) | PTGDR2 | |
| SCHEMBL1901890 | 0.81 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL1901892 | 0.81 | PTGDR2 (0.53) | PTGDR2 | |
| SCHEMBL1903879 | 0.81 | PTGDR2 (0.56) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |