Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1071250 | 0.84 | GPR119 (0.61) | GPR119KCNH2CYP2C9PIK3CDSMN1; SMN2 | |
| SCHEMBL1071139 | 0.81 | GPR119 (0.62) | GPR119KCNH2CYP2C9SCN5ASCN9A | |
| SCHEMBL1243451 | 0.79 | GPR119 (0.53) | GPR119KCNH2CYP2C9PIK3CDSMN1; SMN2 | |
| SCHEMBL5208216 | 0.78 | GPR119 (0.81) | GPR119KCNH2CYP2C9 | |
| SCHEMBL5645093 | 0.77 | GPR119 (0.65) | GPR119KCNH2CYP2C9 | |
| SCHEMBL288589 | 0.77 | GPR119 (0.80) | GPR119KCNH2CYP2C9 | |
| SCHEMBL27747902 | 0.75 | GPR119 (0.62) | GPR119KCNH2CYP2C9SMN1; SMN2ALDH1A1 | |
| SCHEMBL13685456 | 0.75 | GPR119 (0.51) | GPR119KCNH2CYP2C9SMN1; SMN2ALDH1A1 | |
| SCHEMBL4325157 | 0.74 | GPR119 (0.60) | GPR119KCNH2CYP2C9 | |
| SCHEMBL5202632 | 0.73 | GPR119 (0.49) | GPR119KCNH2CYP2C9SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2322152-A1 | Method of preparing a composition comprising a GPR119 agonist | Arena Pharmaceuticals, Inc. (US) | 2011-05-18 | — | — | EP | disclosed |