Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MASP2 | O00187 | 3/20 | 0.43 |
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1904034 | 1.00 | NAMPT (0.46) | NAMPTMEN1KMT2AMASP2FURIN | |
| SCHEMBL1906161 | 1.00 | NAMPT (0.46) | NAMPTMEN1KMT2AMASP2FURIN | |
| SCHEMBL1899808 | 0.89 | PSMB1 (0.43) | NAMPTMASP2FURINKLKB1CPB2 | |
| SCHEMBL1906175 | 0.89 | PSMB1 (0.43) | NAMPTMASP2FURINKLKB1CPB2 | |
| SCHEMBL1902458 | 0.89 | PSMB1 (0.43) | NAMPTMASP2FURINKLKB1CPB2 | |
| SCHEMBL1906713 | 0.88 | ANPEP (0.45) | NAMPTMEN1KMT2AMASP2FURIN | |
| SCHEMBL1904596 | 0.88 | ANPEP (0.45) | NAMPTMEN1KMT2AMASP2FURIN | |
| SCHEMBL1432543 | 0.88 | NAMPT (0.45) | NAMPTMEN1KMT2AMASP2FURIN | |
| SCHEMBL3140017 | 0.88 | NAMPT (0.45) | NAMPTMEN1KMT2AMASP2FURIN | |
| SCHEMBL1432007 | 0.88 | NAMPT (0.46) | NAMPTMEN1KMT2AMASP2FURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051671-A1 | AMINOPYRIDINE DERIVATIVES AS KALLIKREIN INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |