Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.81 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.71 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690730 | 0.83 | TAAR1 (1.00) | MAOBTAAR1ALOX5PNMT | |
| SCHEMBL27900219 | 0.83 | MAOB (0.65) | MAOBTAAR1ALOX5HCAR2 | |
| SCHEMBL28636691 | 0.83 | MAOB (0.65) | MAOBTAAR1ALOX5HCAR2 | |
| Hydrochloric Acid SCHEMBL28279881 | 0.82 | TAAR1 (0.96) | MAOBTAAR1ALOX5PNMT | |
| SCHEMBL4591772 | 0.81 | MAOB (0.73) | MAOBTAAR1AKT2 | |
| SCHEMBL27900185 | 0.80 | MAOB (0.61) | MAOBTAAR1ALOX5HCAR2 | |
| SCHEMBL2026417 | 0.80 | TAAR1 (0.77) | MAOBTAAR1PNMT | |
| SCHEMBL23019492 | 0.79 | TAAR1 (0.51) | MAOBTAAR1AKT2HCAR2 | |
| SCHEMBL416652 | 0.79 | MAOA (0.64) | MAOBTAAR1AKT2 | |
| SCHEMBL15245000 | 0.79 | AKT2 (0.62) | MAOBTAAR1HRH1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2320886-B1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITION FOR THE TREATMENT OF COLLAPSING GLOMERULOPATHY AND OTHER GLOMERULAR DISEASE | GENZYME CORP (US) | 2017-06-28 | — | — | EP | disclosed |