Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900185 | 0.93 | MAOB (0.61) | MAOBTAAR1ALOX5HCAR2MCHR1 | |
| SCHEMBL27882655 | 0.89 | MAOB (0.69) | MAOBTAAR1ALOX5HCAR2MCHR1 | |
| SCHEMBL19043262 | 0.83 | MAOB (0.81) | MAOBTAAR1ALOX5HCAR2 | |
| SCHEMBL28636691 | 0.83 | MAOB (0.65) | MAOBTAAR1ALOX5HCAR2ESR2 | |
| SCHEMBL27900256 | 0.82 | TAAR1 (0.69) | MAOBTAAR1ALOX5HCAR2ESR2 | |
| SCHEMBL900927 | 0.80 | HTR3E (0.59) | TAAR1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL27900188 | 0.79 | MAOB (0.40) | MAOBTAAR1 | |
| SCHEMBL27900194 | 0.79 | TAAR1 (0.65) | MAOBTAAR1HCAR2ESR2GRM2 | |
| SCHEMBL5543001 | 0.79 | FFAR1 (0.50) | MAOBTAAR1 | |
| SCHEMBL7463769 | 0.79 | MAOB (0.69) | MAOBTAAR1ALOX5HCAR2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101277740-B | Antituberculous composition comprising azole compound | OTSUKA PHARMA CO LTD | 2012-12-05 | — | — | CN | disclosed |