Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.42 |
| ▸ | RAB9A | P51151 | 8/20 | 0.42 |
| ▸ | MEN1 | O00255 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.41 |
| ▸ | KCNN1 | Q92952 | 1/20 | 0.41 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.41 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 4/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190619 | 0.94 | ALDH1A1 (0.47) | ALDH1A1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL190492 | 0.92 | RAB9A (0.44) | ALDH1A1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL190878 | 0.85 | KMT2A (0.42) | ALDH1A1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL190565 | 0.85 | RAB9A (0.46) | ALDH1A1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL191303 | 0.83 | KMT2A (0.45) | ALDH1A1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL190971 | 0.83 | KMT2A (0.46) | ALDH1A1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL190235 | 0.82 | RAB9A (0.47) | ALDH1A1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL190400 | 0.80 | RAB9A (0.55) | ALDH1A1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL190920 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KMT2ARAB9AMEN1NPC1 | |
| SCHEMBL190694 | 0.80 | GCK (0.54) | ALDH1A1KMT2ARAB9AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986645-B1 | GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2012-01-04 | — | — | EP | disclosed |
| CN-101437512-A | Glucokinase activators | ARRAY BIOPHARMA INC (US) | 2009-05-20 | — | — | CN | disclosed |