Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22171942 | 0.82 | ALDH1A1 (0.39) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL22197599 | 0.80 | KDM4E (0.52) | KDM4EL3MBTL1ATMDUSP3ALDH1A1 | |
| SCHEMBL18810680 | 0.78 | KDM4E (0.50) | KDM4EL3MBTL1ATMDUSP3ALDH1A1 | |
| SCHEMBL18810663 | 0.77 | L3MBTL1 (0.57) | KDM4EL3MBTL1ATMDUSP3ALDH1A1 | |
| SCHEMBL18810668 | 0.77 | L3MBTL1 (0.52) | KDM4EL3MBTL1ATMDUSP3ALDH1A1 | |
| SCHEMBL19045025 | 0.76 | KDM4E (0.44) | KDM4EL3MBTL1ATMDUSP3ALDH1A1 | |
| SCHEMBL17022454 | 0.76 | KDM4E (0.44) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL22171943 | 0.75 | ALDH1A1 (0.37) | KDM4EL3MBTL1ATMALDH1A1KMT2A | |
| SCHEMBL18810677 | 0.75 | L3MBTL1 (0.53) | KDM4EL3MBTL1ATMDUSP3ALDH1A1 | |
| SCHEMBL15073679 | 0.75 | L3MBTL1 (0.74) | KDM4EL3MBTL1ATMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394062-B1 | HETERO-CONDENSED PHENYLQUINAZOLINES AND THEIR USE IN ELECTRONIC DEVICES | IDEMITSU KOSAN CO (JP) | 2019-10-02 | — | — | EP | disclosed |
| WO-2017109727-A1 | HETERO-CONDENSED PHENYLQUINAZOLINES AND THEIR USE IN ELECTRONIC DEVICES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-29 | — | — | WO | disclosed |