Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20706806 | 0.83 | KDM4E (0.46) | LMNAKMT2AMEN1ALOX5MAPT | |
| SCHEMBL15926552 | 0.82 | ALOX5 (0.44) | LMNAKMT2AMEN1ALOX5MAPT | |
| SCHEMBL18505286 | 0.81 | ALOX5 (0.43) | LMNAKMT2AMEN1ALOX5ALDH1A1 | |
| SCHEMBL23436638 | 0.79 | LMNA (0.39) | LMNAKMT2AMEN1PKMMAPT | |
| SCHEMBL21958286 | 0.79 | ALOX5 (0.43) | LMNAKMT2AMEN1ALOX5MAPT | |
| SCHEMBL14208828 | 0.78 | ALOX5 (0.47) | LMNAALOX5ALDH1A1PRKDCKDM4E | |
| SCHEMBL15926626 | 0.78 | ALOX5 (0.41) | LMNAKMT2AMEN1ALOX5ALDH1A1 | |
| SCHEMBL15926587 | 0.78 | ALOX5 (0.41) | LMNAKMT2AMEN1ALOX5MAPT | |
| SCHEMBL15759657 | 0.78 | ALOX5 (0.46) | LMNAALOX5ALDH1A1PRKDCKDM4E | |
| SCHEMBL17214698 | 0.77 | KDM4E (0.52) | LMNAKMT2AMEN1ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394062-B1 | HETERO-CONDENSED PHENYLQUINAZOLINES AND THEIR USE IN ELECTRONIC DEVICES | IDEMITSU KOSAN CO (JP) | 2019-10-02 | — | — | EP | disclosed |
| WO-2017109727-A1 | HETERO-CONDENSED PHENYLQUINAZOLINES AND THEIR USE IN ELECTRONIC DEVICES | IDEMITSU KOSAN CO., LTD. (JP) | 2017-06-29 | — | — | WO | disclosed |