Gamma-Aminobutyric Acid

Gamma-Aminobutyric Acid

SCHEMBL190459

NCCCC(=O)O.NCCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 1.00
TSHR P16473 3/20 1.00
THRB P10828 2/20 1.00
BLM P54132 2/20 1.00
KMT2A Q03164 2/20 1.00
NPSR1 Q6W5P4 2/20 1.00
GABRR1 P24046 2/20 1.00
GABRR3 A8MPY1 1/20 1.00
GABRP O00591 1/20 1.00
GABRD O14764 1/20 1.00
HDAC3 O15379 1/20 1.00
GABBR2 O75899 1/20 1.00
CYP1A2 P05177 1/20 1.00
GABRA1 P14867 1/20 1.00
GABRB1 P18505 1/20 1.00
GABRG2 P18507 1/20 1.00
GABRB3 P28472 1/20 1.00
GABRR2 P28476 1/20 1.00
SLC6A1 P30531 1/20 1.00
GABRA5 P31644 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 716 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118252237-A Squid slide and preparation method thereof 福州海洋研究院 2024-06-28 CN claimed
US-11951136-B2 Preservation of pancreatic islet grafts in the extrahepatic space THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-04-09 US claimed
CN-117547526-A Application of gamma-aminobutyric acid GABA in preparing medicine for preventing and treating olanzapine-induced adverse reaction 首都医科大学附属北京朝阳医院 2024-02-13 CN claimed
CN-116042483-B Enterococcus faecium FSUH-1 capable of producing gamma-aminobutyric acid and application thereof 佛山科学技术学院 2023-07-18 CN claimed
CN-116042483-A Enterococcus faecium FSUH-1 capable of producing gamma-aminobutyric acid and application thereof 佛山科学技术学院 2023-05-02 CN claimed
CN-113349336-A Low-damage germinated brown rice preparation method and brown rice fine dried noodles preparation method 镇平想念食品有限公司 2021-09-07 CN claimed
CN-113030338-A Method for measuring amino acids in tobacco shreds 贵州中烟工业有限责任公司 2021-06-25 CN claimed
CN-107916232-B Recombined broad spectrum green muscardine fungus and its preparation method and application 中国科学院动物研究所 2019-07-02 CN claimed
US-10338068-B2 Selection of biological objects THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2019-07-02 US claimed
CN-106950383-B Purposes of the spider acetylcholine binding protein in ligand-gated ion channel ligand screening 南京农业大学 2018-09-21 CN claimed
EP-2836485-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS Polyphor Ag (CH) 2015-02-18 EP claimed
CN-101945997-B Method for producing gamma-aminobutyric acid BASF SE 2014-12-03 CN claimed
CN-102559552-B Production method and application of high-yield gamma-aminobutyric acid UNIV TIANJIN SCIENCE & TECH 2014-06-11 CN claimed
WO-2013139697-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2013-09-26 WO claimed
CN-102323340-B Action of pyrro-quinoline quinone and amino acid neurotransmitters JIANGSU INST OF NUCLEAR MED 2013-02-27 CN claimed
US-20120270881-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2012-10-25 US claimed
EP-2499148-A2 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS Polyphor Ag (CH) 2012-09-19 EP claimed
CN-101214022-B Germination coarse rice nutrition powder and production technology thereof UNIV NANJING AGRICULTURAL 2012-07-04 CN claimed
WO-2011014973-A2 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS POLYPHOR AG (CH) 2011-02-10 WO claimed
CN-101214022-A Germination coarse rice nutrition powder and production technology thereof UNIV NANJING AGRICULTURAL (CN) 2008-07-09 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120270881-A1 CONFORMATIONALLY CONSTRAINED, FULLY SYNTHETIC MACROCYCLIC COMPOUNDS KCNB1, KCNAB1, KCNMB1 LMNA 2161/4885TSHR 968/4885THRB 333/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.