Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 17/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19030523 | 0.88 | KMT2A (0.47) | MEN1KMT2ANPSR1IRAK4MAPT | |
| SCHEMBL19029998 | 0.85 | LIN28A (0.47) | MEN1KMT2ANPSR1MAPTPIK3R1 | |
| SCHEMBL19030429 | 0.81 | IRAK4 (0.72) | IRAK4 | |
| SCHEMBL19030072 | 0.77 | EPHX2 (0.49) | MEN1KMT2ANPSR1MAPT | |
| SCHEMBL19029910 | 0.76 | RORC (0.42) | MEN1KMT2ANPSR1 | |
| SCHEMBL349554 | 0.73 | HRH3 (0.48) | MEN1KMT2ANPSR1MAPT | |
| SCHEMBL349555 | 0.73 | HRH3 (0.48) | MEN1KMT2ANPSR1MAPT | |
| SCHEMBL541558 | 0.72 | MEN1 (0.57) | MEN1KMT2ANPSR1 | |
| SCHEMBL15399354 | 0.71 | MEN1 (0.59) | MEN1KMT2ANPSR1MAPT | |
| SCHEMBL15958476 | 0.71 | MEN1 (0.59) | MEN1KMT2ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017108723-A2 | PYRAZOLO[1,5a]PYRIMIDINE DERIVATIVES AS IRAK4 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2017-06-29 | — | — | WO | disclosed |