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Ethylene Glycol

Ethylene Glycol

SCHEMBL1904641

CCCC(COC(C)=O)OCC.OCCO

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.40
▸ LMNA P02545 2/20 0.40
▸ HSD17B10 Q99714 1/20 0.40
▸ PRKCA P17252 5/20 0.38
▸ TSHR P16473 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ PRKCD Q05655 2/20 0.32
▸ PRKCE Q02156 1/20 0.32
▸ PRKCQ Q04759 1/20 0.32
▸ THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5790139 0.94 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10PRKCATSHR
SCHEMBL9615812 0.84 ALDH1A1 (0.45) ALDH1A1LMNAHSD17B10PRKCATSHR
SCHEMBL12582664 0.82 ALDH1A1 (0.52) ALDH1A1LMNAHSD17B10PRKCATSHR
SCHEMBL27497820 0.82 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10PRKCAPRKCD
SCHEMBL7773025 0.81 ALDH1A1 (0.46) ALDH1A1LMNAHSD17B10PRKCATSHR
SCHEMBL1904640 0.79 ALDH1A1 (0.53) ALDH1A1LMNAHSD17B10PRKCATSHR
SCHEMBL28332484 0.79 ALDH1A1 (0.53) ALDH1A1LMNAHSD17B10PRKCATSHR
SCHEMBL144333 0.79 ALDH1A1 (0.48) ALDH1A1LMNAHSD17B10PRKCATSHR
SCHEMBL28327003 0.77 TSHR (0.52) ALDH1A1LMNAHSD17B10TSHRTHRB
SCHEMBL144017 0.77 TDP1 (0.42) ALDH1A1LMNAHSD17B10PRKCATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1960477-B1 NOVEL YELLOW PIGMENTS AND NON-AQUEOUS PIGMENT DISPERSIONS AGFA GRAPHICS NV (BE) 2011-05-04 — — EP disclosed