Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 15/20 | 0.52 |
| ▸ | HTR6 | P50406 | 16/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1904309 | 0.91 | HRH1 (0.62) | HRH1HTR6BCHEGRIN2B | |
| SCHEMBL1905390 | 0.90 | HRH1 (0.53) | HRH1HTR6BCHEGRIN2BADRA2A | |
| SCHEMBL1907947 | 0.90 | HRH1 (0.60) | HRH1HTR6BCHEGRIN2BADRA2A | |
| SCHEMBL1907819 | 0.89 | HRH1 (0.65) | HRH1HTR6BCHEGRIN2BADRA2A | |
| SCHEMBL1903174 | 0.89 | HRH1 (0.52) | HRH1HTR6BCHEGRIN2BADRA2A | |
| SCHEMBL1907946 | 0.88 | HTR6 (0.56) | HRH1HTR6BCHEGRIN2B | |
| SCHEMBL1905300 | 0.87 | HTR6 (0.62) | HRH1HTR6BCHEGRIN2BADRA2A | |
| SCHEMBL1901716 | 0.87 | HTR6 (0.59) | HRH1HTR6BCHE | |
| SCHEMBL1908100 | 0.85 | HRH1 (0.49) | HRH1HTR6BCHEGRIN2B | |
| SCHEMBL1902978 | 0.82 | HRH1 (0.60) | HRH1HTR6BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935823-B2 | Fluoro-containing derivatives of hydrogenated pyrido[4,3-b]indoles with neuroprotective and cognition enhancing properties, process for preparing, and use | D2E, LLC (US) | 2011-05-03 | — | — | US | claimed |
| US-20100056790-A1 | FLUORO-CONTAINING DERIVATIVES OF HYDROGENATED PYRIDO[4,3-B]INDOLES WITH NEUROPROTECTIVE AND COGNITION ENHANCING PROPERTIES, PROCESS FOR PREPARING, AND USE | D2E, LLC (US) | 2010-03-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056790-A1 | FLUORO-CONTAINING DERIVATIVES OF HYDROGENATED PYRIDO[4,3-B]INDOLES WITH NEUROPROTECTIVE AND COGNITION ENHANCING PROPERTIES, PROCESS FOR PREPARING, AND USE | HTR4, SNCA, HTR2B | HRH1 1357/4885HTR6 8/4885BCHE 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.