Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 7/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19042795 | 0.82 | KDM4E (0.36) | KDM4ELMNAABCC2CNR2ALDH1A1 | |
| SCHEMBL19047378 | 0.74 | KDM4E (0.35) | KDM4ELMNAABCC2CNR2ALDH1A1 | |
| SCHEMBL19042799 | 0.74 | CNR2 (0.34) | CNR2ALDH1A1CNR1PSEN1PSEN2 | |
| SCHEMBL19042790 | 0.73 | CNR2 (0.39) | KDM4ELMNAABCC2CNR2ALDH1A1 | |
| SCHEMBL31098897 | 0.63 | GSK3B (0.34) | KDM4ELMNAALDH1A1POLBHTT | |
| SCHEMBL29673705 | 0.60 | CNR2 (0.53) | CNR2CNR1 | |
| SCHEMBL14012059 | 0.58 | CYP2A6 (0.30) | — | |
| SCHEMBL28763406 | 0.58 | KDM4E (0.63) | KDM4ECNR2ALDH1A1CNR1 | |
| SCHEMBL3847894 | 0.58 | PLA2G10 (0.36) | KDM4ELMNAALDH1A1POLBHTT | |
| SCHEMBL9657145 | 0.57 | PGR (0.54) | KDM4ELMNACNR2ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3184096-A1 | DENTAL MATERIALS WITH LIGHT-INDUCED REVERSIBLE COLOURING | Ivoclar Vivadent AG (LI) | 2017-06-28 | — | — | EP | disclosed |