SCHEMBL3847894

SCHEMBL3847894

Cc1sc2ccccc2c1C1=C(c2c(C)n(C)c3ccccc23)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PLA2G10 O15496 1/20 0.36
▸ KDM4E B2RXH2 4/20 0.34
▸ ALDH1A1 P00352 3/20 0.34
▸ HPGD P15428 2/20 0.34
▸ GAA P10253 2/20 0.34
▸ GLA P06280 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ NPSR1 Q6W5P4 2/20 0.33
▸ GPR3 P46089 1/20 0.33
▸ GSK3B P49841 1/20 0.33
▸ POLB P06746 1/20 0.32
▸ HIF1A Q16665 1/20 0.32
▸ MAPT P10636 3/20 0.32
▸ MEN1 O00255 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ TDP1 Q9NUW8 1/20 0.32
▸ LMNA P02545 2/20 0.31
▸ F12 P00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29492999 0.85 GPR3 (0.39) PLA2G10KDM4EALDH1A1HPGDCYP2C19
SCHEMBL392860 0.85 GPR3 (0.39) PLA2G10KDM4EALDH1A1HPGDCYP2C19
SCHEMBL19042790 0.83 CNR2 (0.39) KDM4EALDH1A1HPGDPOLBLMNA
SCHEMBL3848599 0.81 EGFR (0.39) KDM4EALDH1A1HPGDGAAGLA
SCHEMBL3854145 0.80 HIF1A (0.36) KDM4EALDH1A1HPGDGAAGLA
SCHEMBL28661847 0.79 GPR3 (0.39) KDM4EALDH1A1HPGDGAAGLA
SCHEMBL31098897 0.77 GSK3B (0.34) KDM4EALDH1A1HPGDGAAGLA
SCHEMBL3851308 0.77 GSK3B (0.35) HTTNPSR1GSK3BPOLBHIF1A
SCHEMBL9618084 0.75 PLA2G10 (0.33) PLA2G10KDM4EALDH1A1GPR3MAPT
SCHEMBL13889738 0.74 MEN1 (0.39) PLA2G10KDM4EALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5222036-A — — None — — JP disclosed
EP-3732533-B1 SYSTEM AND METHOD FOR CUSTOMIZATION OF A PHOTOCHROMIC ARTICLE TRANSITIONS OPTICAL LTD (IE) 2025-12-10 — — EP disclosed
US-11609442-B2 System and method for customization of a photochromic article TRANSITIONS OPTICAL, LTD. (IE) 2023-03-21 — — US disclosed
US-20210055575-A1 System and Method for Customization of a Photochromic Article TRANSITIONS OPTICAL, LTD. (IE) 2021-02-25 — — US disclosed
EP-3732533-A1 SYSTEM AND METHOD FOR CUSTOMIZATION OF A PHOTOCHROMIC ARTICLE Transitions Optical, Ltd. (IE) 2020-11-04 — — EP disclosed
CN-111527442-A System and method for customizing photochromic articles 光学转变有限公司 2020-08-11 — — CN disclosed
US-8444450-B2 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. (JP) 2013-05-21 — — US disclosed
US-7575386-B2 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. (JP) 2009-08-18 — — US disclosed
EP-1637570-B1 Color-memorizing photochromic writing instrument PILOT INK CO LTD (JP) 2007-06-27 — — EP disclosed
US-20070082977-A1 Ink composition for color-memorizing photochromic writing instrument and writing instrument using the same THE PILOT INK CO., LTD. 2007-04-12 — — US disclosed
EP-1637570-A1 Color-memorizing photochromic writing instrument THE PILOT INK CO., LTD. (JP) 2006-03-22 — — EP disclosed
US-20060053975-A1 Color-memorizing photochromic writing instrument, color-memorizing photochromic writing instrument set using the same and method for alternately expressing color-memorizing photochromic function of writing image THE PILOT INK CO., LTD. 2006-03-16 — — US disclosed
EP-1415692-B1 Method of changing color of a toy and colour changing toy PILOT INK CO LTD (JP) 2005-05-04 — — EP disclosed
US-20040135097-A1 Method for alternately expressing color-memorizing photochromic function in toy element, and an alternately color-memorizing photochromic toy THE PILOT INK CO., LTD. 2004-07-15 — — US disclosed
EP-1415692-A1 Method of changing color of a toy and colour changing toy THE PILOT INK CO., LTD. (JP) 2004-05-06 — — EP disclosed
JP-H05222036-A SULFONATED DIARYLETHENE DERIVATIVE KANEBO LTD 1993-08-31 — — JP disclosed
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