Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19049361 | 0.82 | KDM4E (0.45) | RAB9AKDM4EALDH1A1NPC1EPHX2 | |
| SCHEMBL26224205 | 0.82 | FAAH (0.52) | FAAHALDH1A1DRD2 | |
| SCHEMBL23560471 | 0.81 | FAAH (0.51) | FAAHALDH1A1 | |
| SCHEMBL19049588 | 0.81 | ALDH1A1 (0.44) | RAB9AKDM4EALDH1A1NPC1AKR1C3 | |
| SCHEMBL4546661 | 0.80 | FAAH (0.41) | FAAHALDH1A1EPHX2L3MBTL1 | |
| SCHEMBL19001332 | 0.79 | KDM4E (0.43) | RAB9AKDM4EALDH1A1NPC1AKR1C3 | |
| SCHEMBL25075013 | 0.79 | FAAH (0.50) | FAAHALDH1A1EPHX2L3MBTL1 | |
| SCHEMBL6043717 | 0.79 | ALDH1A1 (0.48) | RAB9AKDM4EALDH1A1NPC1AKR1C3 | |
| SCHEMBL6043709 | 0.79 | ALDH1A1 (0.48) | RAB9AKDM4EALDH1A1NPC1AKR1C3 | |
| SCHEMBL23695831 | 0.79 | FAAH (0.50) | FAAHALDH1A1EPHX2GPR119L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3394056-B1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC (US) | 2021-04-14 | — | — | EP | disclosed |
| WO-2017112777-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC (US) | 2017-06-29 | — | — | WO | disclosed |