SCHEMBL19051318

SCHEMBL19051318

CC(C)OC(=O)/C(C#N)=C\C=C1/CCCN1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 10/20 0.40
▸ ALDH1A1 P00352 8/20 0.38
▸ TP53 P04637 2/20 0.37
▸ MEN1 O00255 10/20 0.36
▸ KMT2A Q03164 10/20 0.36
▸ GAA P10253 7/20 0.36
▸ RAB9A P51151 7/20 0.36
▸ SMN1; SMN2 Q16637 6/20 0.36
▸ PSMD14 O00487 2/20 0.36
▸ LMNA P02545 5/20 0.36
▸ USP2 O75604 4/20 0.36
▸ NPC1 O15118 4/20 0.36
▸ NPSR1 Q6W5P4 3/20 0.36
▸ PTP4A3 O75365 1/20 0.35
▸ PTP4A2 Q12974 1/20 0.35
▸ PTP4A1 Q93096 1/20 0.35
▸ KDM4E B2RXH2 3/20 0.34
▸ HPGD P15428 2/20 0.34
▸ IDE P14735 2/20 0.32
▸ POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19038917 0.82 MAPT (0.55) MAPTALDH1A1TP53MEN1KMT2A
SCHEMBL22477547 0.81 MAPT (0.35) MAPTALDH1A1TP53MEN1KMT2A
SCHEMBL27117352 0.80 MAPT (0.42) MAPTALDH1A1TP53MEN1KMT2A
SCHEMBL19053196 0.79 MEN1 (0.32) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL24390209 0.77 MAPT (0.40) MAPTALDH1A1TP53MEN1KMT2A
SCHEMBL19038893 0.77 MAPT (0.45) MAPTALDH1A1TP53MEN1KMT2A
SCHEMBL23609195 0.76 MAPT (0.39) MAPTALDH1A1TP53MEN1KMT2A
SCHEMBL19051259 0.76 APP (0.46) MAPTALDH1A1TP53MEN1KMT2A
SCHEMBL22477554 0.76 MAPT (0.38) MAPTALDH1A1TP53MEN1KMT2A
SCHEMBL26338677 0.75 MEN1 (0.34) MAPTALDH1A1TP53MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10690824-B2 Optical laminate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-06-23 — — US disclosed
US-20170184766-A1 OPTICAL LAMINATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed
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