SCHEMBL19053196

SCHEMBL19053196

CC(C)OCCC(C)(C)OC(=O)/C(C#N)=C\C=C1/CCCN1C

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 5/20 0.32
▸ MAPT P10636 5/20 0.32
▸ KMT2A Q03164 5/20 0.32
▸ RAB9A P51151 4/20 0.32
▸ GAA P10253 4/20 0.32
▸ SMN1; SMN2 Q16637 3/20 0.32
▸ NPC1 O15118 2/20 0.32
▸ USP2 O75604 2/20 0.32
▸ NPSR1 Q6W5P4 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.30
▸ LMNA P02545 1/20 0.30
▸ PSMD14 O00487 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19051318 0.79 MAPT (0.40) MEN1MAPTKMT2ARAB9AGAA
SCHEMBL19038917 0.75 MAPT (0.55) MEN1MAPTKMT2ARAB9AGAA
SCHEMBL27117352 0.72 MAPT (0.42) MEN1MAPTKMT2ARAB9AGAA
SCHEMBL24390209 0.72 MAPT (0.40) MEN1MAPTKMT2ARAB9AGAA
SCHEMBL19038893 0.72 MAPT (0.45) MEN1MAPTKMT2ARAB9AGAA
SCHEMBL19051259 0.72 APP (0.46) MEN1MAPTKMT2ARAB9AGAA
SCHEMBL23609195 0.72 MAPT (0.39) MEN1MAPTKMT2ARAB9AGAA
SCHEMBL22477547 0.72 MAPT (0.35) MEN1MAPTKMT2ARAB9AGAA
SCHEMBL22477554 0.71 MAPT (0.38) MEN1MAPTKMT2ARAB9AGAA
SCHEMBL26338677 0.69 MEN1 (0.34) MEN1MAPTKMT2ARAB9AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11002896-B2 Retardation film SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-05-11 — — US disclosed
US-10029982-B2 Light absorptive compound, polymer composition containing the compound, polymer film, and cured layer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-07-24 — — US disclosed
US-20170184767-A1 RETARDATION FILM SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed
US-20170183304-A1 LIGHT ABSORPTIVE COMPOUND, POLYMER COMPOSITION CONTAINING THE COMPOUND, POLYMER FILM, AND CURED LAYER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170183304-A1 LIGHT ABSORPTIVE COMPOUND, POLYMER COMPOSITION CONTAINING THE COMPOUND, POLYMER FILM, AND CURED LAYER MLN, MLEC, VIP MEN1 738/4885MAPT 487/4885KMT2A 1715/4885
US-10029982-B2 Light absorptive compound, polymer composition containing the compound, polymer film, and cured layer MLN, MLEC, VIP MEN1 738/4885MAPT 487/4885KMT2A 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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