SCHEMBL19038917

SCHEMBL19038917

CCOC(=O)/C(C#N)=C\C=C1/CCCN1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 11/20 0.55
▸ MEN1 O00255 8/20 0.55
▸ KMT2A Q03164 8/20 0.55
▸ RAB9A P51151 6/20 0.55
▸ NPC1 O15118 5/20 0.55
▸ GAA P10253 4/20 0.55
▸ SMN1; SMN2 Q16637 4/20 0.55
▸ USP2 O75604 3/20 0.55
▸ NPSR1 Q6W5P4 3/20 0.55
▸ ALDH1A1 P00352 11/20 0.52
▸ LMNA P02545 3/20 0.52
▸ CYP2C9 P11712 2/20 0.48
▸ POLB P06746 2/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CYP2D6 P10635 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48
▸ KDM4E B2RXH2 3/20 0.48
▸ HPGD P15428 2/20 0.48
▸ TP53 P04637 1/20 0.48
▸ THRB P10828 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19038893 0.89 MAPT (0.45) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL27117352 0.87 MAPT (0.42) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL24390209 0.84 MAPT (0.40) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL19051259 0.83 APP (0.46) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL23609195 0.83 MAPT (0.39) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL22477554 0.83 MAPT (0.38) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL19240024 0.82 GLO1 (0.41) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL19051318 0.82 MAPT (0.40) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL19038950 0.81 ALDH1A1 (0.44) MAPTMEN1KMT2ARAB9ANPC1
SCHEMBL22477547 0.81 MAPT (0.35) MAPTMEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10690824-B2 Optical laminate SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-06-23 — — US disclosed
US-10029982-B2 Light absorptive compound, polymer composition containing the compound, polymer film, and cured layer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-07-24 — — US disclosed
US-10029982-B2 Light absorptive compound, polymer composition containing the compound, polymer film, and cured layer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-07-24 — — US disclosed
US-20170184766-A1 OPTICAL LAMINATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed
US-20170183304-A1 LIGHT ABSORPTIVE COMPOUND, POLYMER COMPOSITION CONTAINING THE COMPOUND, POLYMER FILM, AND CURED LAYER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed
US-20170184766-A1 OPTICAL LAMINATE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed
US-20170183304-A1 LIGHT ABSORPTIVE COMPOUND, POLYMER COMPOSITION CONTAINING THE COMPOUND, POLYMER FILM, AND CURED LAYER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-06-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170183304-A1 LIGHT ABSORPTIVE COMPOUND, POLYMER COMPOSITION CONTAINING THE COMPOUND, POLYMER FILM, AND CURED LAYER MLN, MLEC, VIP MAPT 487/4885MEN1 738/4885KMT2A 1715/4885
US-10029982-B2 Light absorptive compound, polymer composition containing the compound, polymer film, and cured layer MLN, MLEC, VIP MAPT 487/4885MEN1 738/4885KMT2A 1715/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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