Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Styrene SCHEMBL8352287 | 0.85 | AKR1C3 (0.42) | AKR1C3LMNATSHRALDH1A1HDAC3 | |
| Styrene SCHEMBL7550251 | 0.83 | AKR1C3 (0.52) | AKR1C3LMNATSHRALDH1A1HDAC3 | |
| SCHEMBL6519004 | 0.83 | PTPN1 (0.50) | PTPN1LMNACYP1A2CYP2C9CYP2C19 | |
| Styrene SCHEMBL3141180 | 0.81 | AKR1C3 (0.46) | AKR1C3LMNATSHRALDH1A1HDAC3 | |
| Styrene SCHEMBL393960 | 0.81 | AKR1C3 (0.46) | AKR1C3LMNATSHRALDH1A1HDAC3 | |
| Methacrylic Acid SCHEMBL7949433 | 0.81 | PTPN1 (0.45) | PTPN1LMNAALDH1A1CYP1A2CYP2C9 | |
| Styrene SCHEMBL2042273 | 0.80 | AKR1C3 (0.42) | AKR1C3LMNATSHRALDH1A1HDAC3 | |
| Styrene SCHEMBL8206619 | 0.80 | AKR1C3 (0.42) | AKR1C3LMNATSHRALDH1A1HDAC3 | |
| Styrene SCHEMBL238869 | 0.80 | AKR1C3 (0.59) | AKR1C3LMNATSHRALDH1A1HDAC3 | |
| Styrene SCHEMBL134355 | 0.80 | AKR1C3 (0.59) | AKR1C3LMNATSHRALDH1A1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7935769-B2 | Method for preparing a living polymer comprising methacrylic and/or methacrylate units | ARKEMA FRANCE (FR) | 2011-05-03 | — | — | US | disclosed |
| US-20080306169-A1 | Method For Preparing a Living Polymer Comprising Methacrylic and/or Methacrylate Units | ARKEMA FRANCE (FR) | 2008-12-11 | — | — | US | disclosed |
| US-5264527-A | Block copolymerization using vinylaromatics, methacrylates or acyclics | ELF ATOCHEM S.A. (FR) | 1993-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080306169-A1 | Method For Preparing a Living Polymer Comprising Methacrylic and/or Methacrylate Units | MMAB, ALKBH2, ALKBH3 | AKR1C3 586/4885PTPN1 2851/4885LMNA 964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.