SCHEMBL1905282

SCHEMBL1905282

C=CCOc1c([Si](C)(C)C2c3cc(-c4ccc(CCCC)cc4)ccc3-c3ccc(-c4ccc(CCCC)cc4)cc32)ccc2ccccc12

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MYB P10242 1/20 0.33
PTPN1 P18031 1/20 0.33
DHODH Q02127 1/20 0.33
CNR2 P34972 1/20 0.32
HPGD P15428 1/20 0.31
EIF4A1 P60842 1/20 0.31
MPL P40238 1/20 0.31
CTSV O60911 1/20 0.31
CTSL P07711 1/20 0.31
GAA P10253 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CTSD P07339 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1903096 0.93 MYB (0.35) MYBPTPN1HPGDCTSD
SCHEMBL1903018 0.91 MYB (0.35) MYBHPGD
SCHEMBL1903765 0.89 MYB (0.33) MYBCNR2HPGDGAATDP1
SCHEMBL1902508 0.87 MYB (0.35) MYBHPGDGAA
SCHEMBL1905318 0.86 MYB (0.37) MYBHPGD
SCHEMBL1903639 0.85 HSD11B1 (0.32)
SCHEMBL1904146 0.85 MYB (0.34) MYBHPGD
SCHEMBL1904120 0.84 HSD11B1 (0.33) PTPN1DHODHCNR2
SCHEMBL1901825 0.84 MYB (0.33) MYB
SCHEMBL1907829 0.84 MYB (0.36) MYBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110118427-A1 Transition Metal Complex And Process For Production Thereof, Olefin Polymerization Catalyst, Process For Production of Polyolefin Resin, And Substituted Fluorene Compound And Process For Production Thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2011-05-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110118427-A1 Transition Metal Complex And Process For Production Thereof, Olefin Polymerization Catalyst, Process For Production of Polyolefin Resin, And Substituted Fluorene Compound And Process For Production Thereof FIP1L1, FDFT1, COASY MYB 1175/4885PTPN1 4743/4885DHODH 1111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.