Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903074 | 0.88 | MAPT (0.36) | CYP3A4MAPTALOX15CNR1CASP1 | |
| SCHEMBL1903372 | 0.80 | OPRM1 (0.30) | SLC22A12 | |
| SCHEMBL1352509 | 0.79 | OPRL1 (0.39) | — | |
| SCHEMBL1908041 | 0.78 | CYP3A4 (0.37) | CYP3A4MAPTALOX15CNR1CASP1 | |
| SCHEMBL2030849 | 0.77 | OPRL1 (0.38) | — | |
| SCHEMBL2508530 | 0.75 | OPRL1 (0.42) | — | |
| SCHEMBL1901534 | 0.74 | — | — | |
| Carbamic Acid SCHEMBL1908497 | 0.73 | IP6K1 (0.37) | MAPTSMN1; SMN2 | |
| SCHEMBL1907601 | 0.72 | — | — | |
| SCHEMBL1905911 | 0.70 | ALDH1A1 (0.33) | MAPTALOX15SMN1; SMN2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055115-A1 | AKT / PKB INHIBITORS | ALMAC DISCOVERY LIMITED (GB) | 2011-05-12 | — | — | WO | disclosed |