Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9940683 | 0.74 | HTR5A (0.39) | TNKSTNKS2 | |
| SCHEMBL15812201 | 0.70 | TNKS (0.49) | TNKSTNKS2 | |
| SCHEMBL31159070 | 0.70 | TNKS (0.48) | TNKSTNKS2 | |
| SCHEMBL17436480 | 0.70 | AHR (0.42) | TNKSTNKS2 | |
| SCHEMBL31191321 | 0.70 | PDE7A (0.46) | — | |
| SCHEMBL17436008 | 0.69 | RARB (0.44) | — | |
| SCHEMBL25234677 | 0.68 | HTR5A (0.40) | TNKSTNKS2 | |
| SCHEMBL17436019 | 0.68 | ALDH1A1 (0.47) | — | |
| SCHEMBL1011970 | 0.68 | MAPT (0.52) | — | |
| SCHEMBL19029408 | 0.67 | TNKS (0.34) | TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017108203-A1 | NOVEL SUBSTITUTED INDOLINE COMPOUNDS AS PHOSPHODIESTERASE INHIBITORS | Grünenthal GmbH (DE) | 2017-06-29 | — | — | WO | disclosed |