Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 2/20 | 0.59 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | CCND1 | P24385 | 1/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 7/20 | 0.52 |
| ▸ | KIF11 | P52732 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819077 | 0.93 | TDO2 (0.56) | TDO2IDO1CDK4CCND1PARP14 | |
| SCHEMBL30826547 | 0.93 | TDO2 (0.56) | TDO2IDO1CDK4CCND1PARP14 | |
| SCHEMBL27194803 | 0.91 | TDO2 (0.51) | TDO2IDO1CDK4CCND1PARP14 | |
| SCHEMBL29407801 | 0.91 | KIF11 (0.57) | TDO2CDK4CCND1PARP14KIF11 | |
| SCHEMBL38828 | 0.91 | KIF11 (0.57) | TDO2CDK4CCND1PARP14KIF11 | |
| SCHEMBL208888 | 0.91 | KIF11 (0.57) | TDO2CDK4CCND1PARP14KIF11 | |
| SCHEMBL1326376 | 0.91 | KIF11 (0.57) | TDO2CDK4CCND1PARP14KIF11 | |
| SCHEMBL30641449 | 0.91 | KIF11 (0.57) | TDO2CDK4CCND1PARP14KIF11 | |
| SCHEMBL30815931 | 0.91 | TDO2 (0.54) | TDO2IDO1CDK4CCND1PARP14 | |
| SCHEMBL30815979 | 0.91 | TDO2 (0.54) | TDO2IDO1CDK4CCND1PARP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609867-B1 | CARBAZOLE COMPOUNDS AND METHODS OF USE THEREOF | GSNO THERAPEUTICS INC (US) | 2024-05-15 | — | — | EP | disclosed |
| WO-2017111389-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DIODE INCLUDING SAME | 주식회사 두산 | 2017-06-29 | — | — | WO | disclosed |
| CN-104370801-A | Carbazole compound, and use therefor | TOSOH CORP | 2015-02-25 | — | — | CN | disclosed |
| CN-104326968-A | Carbazole compound and use thereof | TOSOH CORP | 2015-02-04 | — | — | CN | disclosed |
| CN-102666487-B | Carbazole compound and use thereof | TOSOH CORP | 2014-11-05 | — | — | CN | disclosed |
| CN-104011022-A | 4-aminocarbazole compound and use of same | TOSOH CORP | 2014-08-27 | — | — | CN | disclosed |