Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 6/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.57 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6513356 | 0.80 | GAA (0.54) | GRM2 | |
| SCHEMBL19061902 | 0.80 | SPR (0.48) | CHRM2CHRM1CHRM3 | |
| SCHEMBL5101834 | 0.78 | CHRM2 (0.66) | ABCB1ABCG2CHRM2CHRM1CHRM3 | |
| SCHEMBL27923029 | 0.77 | CHRM2 (0.60) | ABCB1ABCG2CHRM2CHRM1CHRM3 | |
| SCHEMBL19062086 | 0.77 | CHRM2 (0.60) | CHRM2CHRM1CHRM3MTNR1AMTNR1B | |
| SCHEMBL28803519 | 0.77 | CHRM2 (0.60) | ABCB1ABCG2CHRM2CHRM1CHRM3 | |
| SCHEMBL27907664 | 0.77 | ABCB1 (0.68) | ABCB1ABCG2GRM2 | |
| SCHEMBL5524054 | 0.76 | CHRM2 (0.68) | ABCB1ABCG2CHRM2CHRM1CHRM3 | |
| SCHEMBL19061666 | 0.76 | TAAR1 (0.52) | ABCB1ABCG2 | |
| SCHEMBL19061903 | 0.76 | POLB (0.71) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10398689-B2 | Benzopiperidine derivative, preparation method thereof and medical use thereof | JIANGSU HENGRUI MEDICINE CO., LTD. (CN) | 2019-09-03 | — | — | US | disclosed |
| WO-2017107754-A1 | BENZOPIPERIDINE DERIVATIVE, PREPARATION METHOD THEREOF AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2017-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10398689-B2 | Benzopiperidine derivative, preparation method thereof and medical use thereof | CYP19A1, BRCA1, GPER1 | ABCB1 53/4885ABCG2 319/4885CHRM2 1014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.