Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KDM6B | O15054 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084522 | 0.89 | HDAC6 (0.51) | GAAL3MBTL1GRM2MEN1KMT2A | |
| SCHEMBL8093196 | 0.88 | L3MBTL1 (0.53) | GAAL3MBTL1GRM2MEN1KMT2A | |
| SCHEMBL30806170 | 0.84 | MAPT (0.54) | GAAMAPTMEN1KMT2AHDAC8 | |
| SCHEMBL19061902 | 0.82 | SPR (0.48) | GAAMAPTTAAR1PKMALDH1A1 | |
| SCHEMBL19495506 | 0.82 | HSD17B10 (0.53) | GAAL3MBTL1GRM2KDM4EHDAC8 | |
| Hydrochloric Acid SCHEMBL2343034 | 0.82 | MAPT (0.52) | GAAMAPTMEN1KMT2AHDAC8 | |
| SCHEMBL893345 | 0.81 | HSD17B10 (0.60) | GAAL3MBTL1GRM2KDM4EHDAC8 | |
| SCHEMBL2917100 | 0.80 | POLB (0.50) | GAAMAPTMEN1KMT2AHDAC8 | |
| Hydrochloric Acid SCHEMBL28633352 | 0.80 | POLB (0.53) | MAPTTAAR1MEN1KMT2AKDM4E | |
| SCHEMBL19061908 | 0.80 | ABCB1 (0.65) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005077885-A1 | RUTHENIUM-CATALYZED HYDROAMINATION OF OLEFINS | YALE UNIVERSITY (US) | 2005-08-25 | — | — | WO | disclosed |