SCHEMBL1906266

SCHEMBL1906266

O=P(O)(O)C(Br)P(=O)(O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
MMP2 P08253 1/20 0.38
THRB P10828 1/20 0.38
MAPK1 P28482 1/20 0.38
HSD17B10 Q99714 1/20 0.38
LAP3 P28838 2/20 0.33
ANPEP P15144 1/20 0.33
ERAP2 Q6P179 1/20 0.33
TYMS P04818 1/20 0.33
CA2 P00918 1/20 0.33
FDPS P14324 2/20 0.32
SLC34A1 Q06495 1/20 0.31
CA12 O43570 1/20 0.31
CA9 Q16790 1/20 0.31
PGK1 P00558 3/20 0.30
PGK2 P07205 3/20 0.30
GABBR2 O75899 1/20 0.30
GABBR1 Q9UBS5 1/20 0.30
MEN1 O00255 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4409893 0.78
SCHEMBL1584494 0.72
SCHEMBL10425747 0.67
Phosphoric Acid SCHEMBL27971573 0.66 CA2 (0.50) KDM4EMMP2THRBMAPK1HSD17B10
Phosphoric Acid SCHEMBL83112 0.66
Phosphoric Acid SCHEMBL9617774 0.66 CA2 (0.50) KDM4EMMP2THRBMAPK1HSD17B10
Phosphoric Acid SCHEMBL4294414 0.66 CA2 (0.50) KDM4EMMP2THRBMAPK1HSD17B10
Phosphoric Acid SCHEMBL27941021 0.66
SCHEMBL919194 0.64
SCHEMBL1409859 0.64 KDM4E (0.43) KDM4EMMP2THRBMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118146259-A Iron ion stabilizer for oilfield acidification and synthesis method thereof 山东滨州昱诚化工科技有限公司 2024-06-07 CN claimed
CN-117430634-A Iron ion stabilizer for acidizing and fracturing and preparation method thereof 滨州市广友石油科技有限公司 2024-01-23 CN claimed
CN-118146259-A Iron ion stabilizer for oilfield acidification and synthesis method thereof 山东滨州昱诚化工科技有限公司 2024-06-07 CN disclosed
CN-118146259-A Iron ion stabilizer for oilfield acidification and synthesis method thereof 山东滨州昱诚化工科技有限公司 2024-06-07 CN disclosed
CN-117430634-A Iron ion stabilizer for acidizing and fracturing and preparation method thereof 滨州市广友石油科技有限公司 2024-01-23 CN disclosed
CN-117430634-A Iron ion stabilizer for acidizing and fracturing and preparation method thereof 滨州市广友石油科技有限公司 2024-01-23 CN disclosed
US-9265751-B2 Methods for treating chronic pain NAGASAKI UNIVERSITY (JP) 2016-02-23 US disclosed
WO-2015193669-A1 DIAGNOSTIC AND THERAPEUTIC METHOD INVOLVING THE AUTOTAXIN-LYSOPHOSPHATIDIC ACID SIGNALLING PATHWAY BABRAHAM INSTITUTE (GB) 2015-12-23 WO disclosed
EP-2324852-B1 THERAPEUTIC OR PROPHYLACTIC AGENT FOR GENERALIZED PAIN SYNDROME UNIV NAGASAKI (JP) 2015-07-08 EP disclosed
US-20150087812-A1 Human Autotaxin Antibodies and Methods of Use JANSSEN BIOTECH, INC. (US) 2015-03-26 US disclosed
EP-2825199-A1 HUMAN AUTOTAXIN ANTIBODIES AND METHODS OF USE Janssen Biotech, Inc. (US) 2015-01-21 EP disclosed
EP-0570380-A1 NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES LEIRAS OY (FI) 1993-11-24 EP disclosed
WO-1992011268-A1 NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES LEIRAS OY (FI) 1992-07-09 WO disclosed
EP-0479813-A1 NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES. HUHTAMAEKI YHTHYMAE OY (FI) 1992-04-15 EP disclosed
WO-1990015806-A1 NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES Huhtamäki Oy (FI) 1990-12-27 WO disclosed
US-4579720-A USING HYDROXYMETHANE DIPHOSPHONIC ACID PLAINS CHEMICAL DEVELOPMENT CO. (US) 1986-04-01 US disclosed
US-4440646-A HYDROXY OR HALOALKANEPHOSPHONATES PLAINS CHEMICAL DEVELOPMENT CO. (US) 1984-04-03 US disclosed
US-4188234-A STABILIZATION OF VINYL POLYMERS, POLYPHOSPHONIC ACID CHELATING AGENT, PROTECTIVE COATINGS PLAINS CHEMICAL DEVELOPMENT CO. (US) 1980-02-12 US disclosed
US-4116990-A OF NON-ALKALI METAL IONS WITH PHOSPHORUS CHELATING COMPOUND PLAINS CHEMICAL DEVELOPMENT CO. (US) 1978-09-26 US disclosed
US-4020091-A TIN SALTS OF POLYPHOSPHONIC ACIDS PLAINS CHEMICAL DEVELOPMENT CO. (US) 1977-04-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150087812-A1 Human Autotaxin Antibodies and Methods of Use ENPP2, PLA2G12A, ABHD16A KDM4E 3540/4885MMP2 401/4885THRB 3602/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.