Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | PPOX | P50336 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19062416 | 1.00 | TERT (0.40) | TERTMEN1KMT2AUSP2KEAP1 | |
| SCHEMBL19062681 | 0.92 | TERT (0.45) | TERTMEN1KMT2AUSP2KEAP1 | |
| SCHEMBL19062676 | 0.92 | TERT (0.45) | TERTMEN1KMT2AUSP2KEAP1 | |
| SCHEMBL19062417 | 0.88 | TERT (0.33) | TERTMEN1KMT2AUSP2POLB | |
| SCHEMBL19052074 | 0.84 | STAT3 (0.44) | TERTMEN1KMT2AUSP2STAT3 | |
| SCHEMBL19052062 | 0.84 | STAT3 (0.44) | TERTMEN1KMT2AUSP2STAT3 | |
| SCHEMBL12748863 | 0.83 | TERT (0.49) | TERTMEN1KMT2AUSP2KEAP1 | |
| SCHEMBL19472282 | 0.83 | TERT (0.49) | TERTMEN1KMT2AUSP2KEAP1 | |
| SCHEMBL19062802 | 0.82 | TERT (0.30) | TERT | |
| SCHEMBL19062421 | 0.80 | TERT (0.36) | TERTMEN1KMT2AUSP2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170186961-A1 | ORGANIC SEMICONDUCTOR COMPOUNDS AND METHODS OF USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-06-29 | — | — | US | disclosed |