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SCHEMBL19062681

SCHEMBL19062681

CN1C(=O)c2ccc3c4ccc5c6c(cc(/C=C/c7cc8c9c(ccc%10c%11c(/C=C/c%12cc%13c%14c(ccc%15c%16ccc%17c%18c(ccc(c%12c%14%15)c%18%16)C(=O)N(C)C%17=O)C(=O)N(C)C%13=O)cc%12c%13c(ccc(c7c9%10)c%13%11)C(=O)N(C)C%12=O)C(=O)N(C)C8=O)c(c7ccc(c2c37)C1=O)c64)C(=O)N(C)C5=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 8/20 0.45
▸ STAT3 P40763 1/20 0.40
▸ HIF1A Q16665 1/20 0.40
▸ MEN1 O00255 5/20 0.40
▸ KMT2A Q03164 5/20 0.40
▸ ALDH1A1 P00352 4/20 0.40
▸ USP2 O75604 2/20 0.40
▸ KEAP1 Q14145 2/20 0.40
▸ NFE2L2 Q16236 2/20 0.40
▸ HPGD P15428 2/20 0.40
▸ ATM Q13315 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.40
▸ POLB P06746 1/20 0.38
▸ PRMT1 Q99873 1/20 0.38
▸ MAPT P10636 2/20 0.34
▸ HSD17B10 Q99714 2/20 0.34
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ ALOX15 P16050 1/20 0.34
▸ APP P05067 2/20 0.33
▸ MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19062676 1.00 TERT (0.45) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL19062416 0.92 TERT (0.40) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL19062794 0.92 TERT (0.40) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL19062421 0.87 TERT (0.36) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL21726086 0.85 STAT3 (0.47) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL19062803 0.85 TERT (0.35) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL21726085 0.84 TERT (0.39) TERTSTAT3HIF1A
SCHEMBL23665436 0.83 MEN1 (0.35) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL9968958 0.81 TERT (0.56) TERTSTAT3HIF1AMEN1KMT2A
SCHEMBL9968962 0.81 TERT (0.56) TERTSTAT3HIF1AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10566539-B2 Organic semiconductor compounds and methods of use THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2020-02-18 — — US disclosed
US-20170186961-A1 ORGANIC SEMICONDUCTOR COMPOUNDS AND METHODS OF USE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2017-06-29 — — US disclosed
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