Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.39 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662919 | 0.81 | KMT2A (0.68) | KMT2ACYP19A1HPGDSLC2A1ALDH1A1 | |
| SCHEMBL214075 | 0.80 | KMT2A (1.00) | KMT2ACYP19A1HPGDALDH1A1APP | |
| SCHEMBL29581156 | 0.80 | KMT2A (1.00) | KMT2ACYP19A1HPGDALDH1A1APP | |
| SCHEMBL2382803 | 0.79 | KMT2A (0.66) | KMT2ACYP19A1HPGDSLC2A1ALDH1A1 | |
| SCHEMBL11688437 | 0.79 | KMT2A (0.66) | KMT2ACYP19A1HPGDSLC2A1ALDH1A1 | |
| SCHEMBL8942357 | 0.79 | KMT2A (0.66) | KMT2ACYP19A1HPGDSLC2A1ALDH1A1 | |
| SCHEMBL2421377 | 0.79 | KMT2A (0.66) | KMT2ACYP19A1HPGDSLC2A1ALDH1A1 | |
| SCHEMBL8942111 | 0.77 | GRIK1 (0.67) | KMT2ACYP19A1HPGDALDH1A1KDM4E | |
| SCHEMBL11687991 | 0.77 | KMT2A (0.92) | KMT2ACYP19A1HPGDALDH1A1APP | |
| SCHEMBL8305794 | 0.77 | KMT2A (0.72) | KMT2ACYP19A1HPGDSLC2A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598486-B1 | BICYCLIC ACETYL-COA CARBOXYLASE INHIBITORS | NOVARTIS AG (CH) | 2017-06-28 | — | — | EP | disclosed |