Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.57 |
| ▸ | ACLY | P53396 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7799883 | 0.89 | KMT2A (0.50) | KMT2ACYP19A1ACLYALDH1A1HPGD | |
| SCHEMBL11688348 | 0.86 | KMT2A (0.66) | KMT2ACYP19A1ACLYALDH1A1HPGD | |
| SCHEMBL22004394 | 0.83 | KCNH2 (0.48) | KMT2ACYP19A1ACLYPHGDHMEN1 | |
| SCHEMBL22003808 | 0.83 | ACLY (0.49) | KMT2ACYP19A1ACLYALDH1A1MEN1 | |
| SCHEMBL24115004 | 0.82 | AOC3 (0.53) | KMT2ACYP19A1ACLYALDH1A1 | |
| SCHEMBL22004113 | 0.82 | ACLY (0.60) | KMT2ACYP19A1ACLYPHGDH | |
| SCHEMBL22004304 | 0.81 | ACLY (0.63) | KMT2ACYP19A1ACLYPHGDH | |
| SCHEMBL22021620 | 0.81 | ACLY (0.50) | KMT2ACYP19A1ACLYALDH1A1HPGD | |
| SCHEMBL11662919 | 0.81 | KMT2A (0.68) | KMT2ACYP19A1ACLYALDH1A1HPGD | |
| SCHEMBL11658428 | 0.81 | KMT2A (0.73) | KMT2ACYP19A1ALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109467559-B | Fused bisindole derivatives and process for producing the same | 苏州大学 | 2020-02-11 | — | — | CN | claimed |
| CN-109467559-A | Condensed bisindole derivatives and preparation method thereof | 苏州大学 | 2019-03-15 | — | — | CN | claimed |
| CN-109535061-B | 3-nitrosoindole derivative and preparation method thereof | 苏州大学 | 2020-07-14 | — | — | CN | disclosed |
| CN-109467559-B | Fused bisindole derivatives and process for producing the same | 苏州大学 | 2020-02-11 | — | — | CN | disclosed |
| CN-109535061-A | A kind of 3- nitroso-indol derivative and preparation method thereof | 苏州大学 | 2019-03-29 | — | — | CN | disclosed |
| CN-109467559-A | Condensed bisindole derivatives and preparation method thereof | 苏州大学 | 2019-03-15 | — | — | CN | disclosed |
| US-5578711-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-26 | — | — | US | disclosed |
| US-5541299-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-07-30 | — | — | US | disclosed |
| US-5502171-A | Process for the preparation of dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1996-03-26 | — | — | US | disclosed |
| US-5446011-A | Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid | RICOH COMPANY, LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0446731-B1 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1995-05-03 | — | — | EP | disclosed |
| EP-0446731-A2 | Process for the manufacture of azo dyes | BAYER AG (DE) | 1991-09-18 | — | — | EP | disclosed |
| US-4104268-A | POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |