SCHEMBL214075

SCHEMBL214075

Cn1c(-c2ccccc2)cc2ccccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 1.00
APP P05067 4/20 0.59
ALDH1A1 P00352 4/20 0.58
HPGD P15428 3/20 0.58
KDM4E B2RXH2 2/20 0.58
MEN1 O00255 1/20 0.58
MAPT P10636 1/20 0.58
RECQL P46063 1/20 0.58
CYP19A1 P11511 1/20 0.57
MCL1 Q07820 1/20 0.52
HSD17B10 Q99714 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
ADRA2A P08913 1/20 0.50
TERT O14746 1/20 0.47
DAO P14920 1/20 0.47
FASN P49327 1/20 0.47
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29581156 1.00 KMT2A (1.00) KMT2AAPPALDH1A1HPGDKDM4E
SCHEMBL11687991 0.96 KMT2A (0.92) KMT2AAPPALDH1A1HPGDKDM4E
SCHEMBL8304311 0.90 KMT2A (0.81) KMT2AAPPALDH1A1HPGDKDM4E
SCHEMBL10103705 0.87 KMT2A (0.76) KMT2AAPPALDH1A1HPGDKDM4E
SCHEMBL11809642 0.87 KMT2A (0.75) KMT2AAPPALDH1A1HPGDKDM4E
SCHEMBL11809637 0.87 KMT2A (0.75) KMT2AAPPALDH1A1HPGDKDM4E
SCHEMBL3686929 0.86 KMT2A (0.76) KMT2AAPPALDH1A1HPGDKDM4E
SCHEMBL20476723 0.85 KMT2A (0.73) KMT2AAPPALDH1A1HPGDKDM4E
SCHEMBL11688009 0.85 KMT2A (0.73) KMT2AAPPALDH1A1HPGDKDM4E
SCHEMBL8591982 0.85 KMT2A (0.73) KMT2AAPPALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 822 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368351-B Preparation method and application of polysubstituted oxazole compound 广东工业大学 2025-03-25 CN claimed
CN-119409615-A 2- (Indol-3-yl) phenol compound and synthesis method thereof 湘潭大学 2025-02-11 CN claimed
CN-117886736-A 2-indolyl-3-imine indoline derivative, preparation method and application thereof 苏州昊帆生物股份有限公司 2024-04-16 CN claimed
CN-113201526-B Difunctional photo-enzyme synergistic catalyst and preparation method and application thereof 东南大学 2024-04-09 CN claimed
CN-117384080-A Synthesis method of N-methyl-2-phenylindole 南京工业大学 2024-01-12 CN claimed
CN-116239938-A High-adhesion solder resist coating and preparation process thereof 江苏海田电子材料有限公司 2023-06-09 CN claimed
CN-109400518-B Polysubstituted 6-arylbenzo [ a ] carbazole derivative and synthetic method thereof 湘潭大学 2021-09-24 CN claimed
CN-113201526-A Bifunctional photo-enzyme synergistic catalyst and preparation method and application thereof 东南大学 2021-08-03 CN claimed
CN-109467559-B Fused bisindole derivatives and process for producing the same 苏州大学 2020-02-11 CN claimed
CN-104649854-A Cheap and efficient preparation method of aryl halides UNIV BEIJING 2015-05-27 CN claimed
EP-0650599-A1 METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION OXIS INTERNATIONAL S.A. (FR) 1995-05-03 EP claimed
WO-1994027155-A1 METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION BIOXYTECH (FR) 1994-11-24 WO claimed
US-5334642-A Includes organic compound which has a base constant within the range 2 to 12 and boiling point higher than 300 degrees BASF AKTIENGESELLSCHAFT (DE) 1994-08-02 US claimed
US-5208278-A STABILIZED POLYARYL ETHER KETONE MOLDING COMPOSITIONS BASF AKTIENGESELLSCHAFT (DE) 1993-05-04 US claimed
EP-0451556-A2 Stabilised polyaryletherketone - moulding compounds BASF Aktiengesellschaft (DE) 1991-10-16 EP claimed
US-5013707-A Pressure- or heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1991-05-07 US claimed
US-4925901-A STORAGE STAABILITY, ONIUM ION CATALYST THE DOW CHEMICAL COMPANY (US) 1990-05-15 US claimed
US-4843151-A RED/YELLOW DYES FOR NATURAL AND SYNTHETIC POLYAMIDES USING AN AQUEOUS BATH; COLORFASTNESS CIBA-GEIGY CORPORATION (US) 1989-06-27 US claimed
EP-0062607-B1 MONOAZO DYESTUFFS, THEIR PRAPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1986-04-23 EP claimed
US-4003747-A Photosensitive azide compound containing color-forming element HODOGAYA CHEMICAL CO., LTD. (JA) 1977-01-18 US claimed