Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNB1 | Q14721 | 4/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LCLAT1 | Q6UWP7 | 9/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.35 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31239067 | 1.00 | KCNB1 (0.41) | KCNB1KCNA5KCNH2MAPTMEN1 | |
| Difamilast SCHEMBL4275421 | 0.91 | HPGD (0.44) | KCNB1KCNA5KCNH2MAPTMEN1 | |
| Difamilast SCHEMBL29372760 | 0.91 | HPGD (0.44) | KCNB1KCNA5KCNH2MAPTMEN1 | |
| SCHEMBL4276921 | 0.91 | HPGD (0.44) | KCNB1KCNA5KCNH2MAPTMEN1 | |
| Difamilast SCHEMBL30978541 | 0.91 | HPGD (0.44) | KCNB1KCNA5KCNH2MAPTMEN1 | |
| SCHEMBL19066419 | 0.91 | NAAA (0.34) | LMNAKMT2ALCLAT1TSHRSMN1; SMN2 | |
| SCHEMBL19066415 | 0.89 | ADRB1 (0.33) | MEN1KMT2ALCLAT1SMN1; SMN2 | |
| SCHEMBL31238992 | 0.88 | KCNB1 (0.43) | KCNB1KCNA5KCNH2KMT2ASMN1; SMN2 | |
| SCHEMBL19066426 | 0.88 | KCNB1 (0.43) | KCNB1KCNA5KCNH2KMT2ASMN1; SMN2 | |
| SCHEMBL4271337 | 0.87 | HPGD (0.47) | KCNB1KCNA5KCNH2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240366573-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-11-07 | — | — | US | disclosed |
| US-20220117944-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-04-21 | — | — | US | disclosed |
| US-20220117944-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-04-21 | — | — | US | disclosed |
| US-20200171006-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-20200171006-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-06-04 | — | — | US | disclosed |
| US-10588893-B2 | Ointment containing an oxazole compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-03-17 | — | — | US | disclosed |
| US-10588893-B2 | Ointment containing an oxazole compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-03-17 | — | — | US | disclosed |
| US-20190000810-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| US-20190000810-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2019-01-03 | — | — | US | disclosed |
| EP-3397619-A1 | OINTMENT | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-11-07 | — | — | EP | disclosed |
| WO-2017115780-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-07-06 | — | — | WO | disclosed |
| WO-2017115780-A1 | OINTMENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-07-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240366573-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | PDE12, PDE4B, PDE4A | KCNB1 3004/4885KCNA5 2403/4885KCNH2 3365/4885 |
| US-20200171006-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | PDE12, PDE4B, PDE4A | KCNB1 3004/4885KCNA5 2403/4885KCNH2 3365/4885 |
| US-20220117944-A1 | OINTMENT CONTAINING AN OXAZOLE COMPOUND | PDE12, PDE4B, PDE4A | KCNB1 3004/4885KCNA5 2403/4885KCNH2 3365/4885 |
| US-10588893-B2 | Ointment containing an oxazole compound | PDE12, PDE4B, PDE4A | KCNB1 3004/4885KCNA5 2403/4885KCNH2 3365/4885 |
| US-20190000810-A1 | OINTMENT | PDE12, PDE4B, PDE4A | KCNB1 3422/4885KCNA5 3117/4885KCNH2 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.