Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.42 |
| ▸ | MRGPRX2 | Q96LB1 | 3/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14501894 | 0.88 | OPRD1 (0.56) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL19068368 | 0.84 | OPRD1 (0.44) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL19068356 | 0.83 | OPRD1 (0.59) | OPRD1OPRM1OPRK1 | |
| SCHEMBL14501896 | 0.83 | OPRM1 (0.55) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL14501897 | 0.81 | OPRM1 (0.55) | OPRD1OPRM1OPRK1MRGPRX2 | |
| SCHEMBL16126166 | 0.77 | OPRD1 (0.58) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| SCHEMBL30948834 | 0.77 | OPRD1 (0.58) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL16922136 | 0.76 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL16922130 | 0.76 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL17302926 | 0.76 | OPRD1 (0.81) | OPRD1OPRM1OPRK1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9694069-B2 | 6-acetylmorphine analogs, and methods for their synthesis and use | ALERE SAN DIEGO, INC. (US) | 2017-07-04 | — | — | US | disclosed |