Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 4/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | LIPE | Q05469 | 4/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20264628 | 0.81 | PDGFRB (0.39) | CXCR2LIPE | |
| SCHEMBL14800589 | 0.80 | CCR1 (0.32) | LPLLIPGFFAR1 | |
| SCHEMBL31378591 | 0.79 | LPL (0.39) | CXCR2LPLLIPGEGFR | |
| SCHEMBL17752336 | 0.79 | LPL (0.39) | CXCR2LPLLIPGEGFR | |
| SCHEMBL16094541 | 0.76 | PDGFRB (0.31) | — | |
| SCHEMBL15923768 | 0.76 | EGFR (0.33) | LIPEEGFR | |
| SCHEMBL22657170 | 0.76 | FFAR1 (0.32) | FFAR1 | |
| SCHEMBL30236983 | 0.76 | PDGFRB (0.31) | — | |
| SCHEMBL16533879 | 0.74 | USP30 (0.39) | — | |
| SCHEMBL27050551 | 0.73 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9694016-B2 | Biaryl amide compounds as kinase inhibitors | NOVARTIS AG (CH) | 2017-07-04 | — | — | US | disclosed |