Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17752336 | 1.00 | LPL (0.39) | LPLLIPGCXCR2JAK2BTK | |
| SCHEMBL15393439 | 0.86 | LPL (0.41) | LPLLIPGCXCR2JAK2BTK | |
| SCHEMBL14800589 | 0.84 | CCR1 (0.32) | LPLLIPG | |
| SCHEMBL30508645 | 0.81 | LPL (0.38) | LPLLIPGCXCR2JAK2BTK | |
| SCHEMBL15392968 | 0.81 | LPL (0.38) | LPLLIPGCXCR2JAK2BTK | |
| SCHEMBL21911080 | 0.81 | LPL (0.38) | LPLLIPGCXCR2JAK2BTK | |
| SCHEMBL22657170 | 0.79 | FFAR1 (0.32) | — | |
| SCHEMBL30236983 | 0.79 | PDGFRB (0.31) | — | |
| SCHEMBL16094541 | 0.79 | PDGFRB (0.31) | — | |
| SCHEMBL15923768 | 0.79 | EGFR (0.33) | JAK2BTKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038395-A1 | BENZOPYRIDINONES AND BENZOPYRIMIDINONES AS PI3K INHIBITORS | ONKURE, INC. (US) | 2025-02-20 | — | — | WO | disclosed |