Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 3/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.32 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256579 | 0.88 | METAP1 (0.39) | CYP26A1CYP24A1CYP19A1LMNAMEN1 | |
| SCHEMBL19070884 | 0.84 | ACACB (0.36) | ESR2ESR1CYP26A1CYP24A1CYP19A1 | |
| SCHEMBL19071419 | 0.82 | MEN1 (0.34) | ESR2ESR1CYP26A1CYP24A1CYP19A1 | |
| SCHEMBL19070695 | 0.80 | HSD17B1 (0.36) | ESR2ESR1TYRHSD17B1CYP19A1 | |
| SCHEMBL19070317 | 0.78 | OPRL1 (0.33) | CYP26A1CYP19A1 | |
| SCHEMBL19071000 | 0.76 | DRD4 (0.33) | — | |
| SCHEMBL16256578 | 0.72 | ACHE (0.41) | CYP26A1CYP24A1CYP19A1MEN1KMT2A | |
| SCHEMBL19071282 | 0.71 | METAP1 (0.32) | CYP24A1 | |
| SCHEMBL16256588 | 0.71 | CNR2 (0.38) | CYP26A1CYP24A1MEN1KMT2AALDH1A1 | |
| SCHEMBL16256577 | 0.71 | ACHE (0.52) | CYP26A1CYP24A1CYP19A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |