Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 13/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905993 | 1.00 | FFAR2 (0.47) | FFAR2BRD4PRCPADRB2HDAC4 | |
| SCHEMBL1905919 | 0.91 | CYP2C9 (0.41) | FFAR2 | |
| SCHEMBL1905489 | 0.86 | FFAR2 (0.47) | FFAR2BRD4PRCPADRB2 | |
| SCHEMBL22491784 | 0.86 | FFAR2 (0.47) | FFAR2BRD4PRCPADRB2 | |
| SCHEMBL9899646 | 0.86 | FFAR2 (0.47) | FFAR2BRD4PRCPADRB2 | |
| SCHEMBL1906571 | 0.86 | FFAR2 (0.47) | FFAR2BRD4PRCPADRB2 | |
| SCHEMBL23509577 | 0.85 | FFAR2 (0.46) | FFAR2BRD4PRCPADRB2 | |
| SCHEMBL6903118 | 0.85 | CES2 (0.44) | — | |
| SCHEMBL6900808 | 0.83 | NR1H4 (0.40) | — | |
| SCHEMBL22491773 | 0.82 | FFAR2 (0.47) | FFAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493845-A1 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2012-09-05 | — | — | EP | disclosed |
| WO-2011051165-A1 | SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-05-05 | — | — | WO | disclosed |