SCHEMBL190727

SCHEMBL190727

CCCCCCCC/C=C\CCCCCCCC(=O)OCC(COC(=O)CCCCCCCCCCCCCCC)OP(=O)(O)OCCN

nearest known ligand 0.71

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.64
RECQL P46063 1/20 0.59
BLM P54132 1/20 0.59
TDP1 Q9NUW8 1/20 0.59
LPAR3 Q9UBY5 1/20 0.59
P2RY10 O00398 4/20 0.59
GPR34 Q9UPC5 1/20 0.59
LPAR1 Q92633 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16714278 1.00 ENPP2 (0.64) ENPP2RECQLBLMTDP1LPAR3
SCHEMBL2126025 0.95 PRKCE (0.61) ENPP2RECQLBLMTDP1LPAR3
SCHEMBL3645476 0.94 ENPP2 (0.57) ENPP2RECQLBLMTDP1LPAR3
SCHEMBL15526366 0.93 ENPP2 (0.59) ENPP2LPAR3LPAR1
SCHEMBL1402383 0.93 ENPP2 (0.59) ENPP2LPAR3LPAR1
SCHEMBL8017848 0.89 ENPP2 (0.60) ENPP2RECQLBLMTDP1LPAR3
SCHEMBL23209666 0.88 SELP (0.71) ENPP2LPAR3P2RY10GPR34LPAR1
SCHEMBL23387627 0.88 SELP (0.71) ENPP2LPAR3P2RY10GPR34LPAR1
SCHEMBL21641453 0.88 SELP (0.71) ENPP2LPAR3P2RY10GPR34LPAR1
SCHEMBL23256430 0.88 SELP (0.71) ENPP2LPAR3P2RY10GPR34LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9610334-B2 Truncated secretory aspartyl proteinase 2 ISTITUTO SUPERIORE DI SANITA (IT) 2017-04-04 US disclosed
EP-2467155-B1 MULTIEPITOPE VACCINE FOR HER2/NEU-ASSOCIATED CANCERS BIOLIFE SCIENCE QLD LTD (AU) 2015-11-11 EP disclosed
US-8852604-B2 Multiepitope vaccine for Her2/neu-associated cancers PEVION BIOTECH AG (CH) 2014-10-07 US disclosed
US-20140193445-A1 Truncated Secretory Aspartyl Proteinase 2 ISTITUTO SUPERIORE DI SANITA (IT) 2014-07-10 US disclosed
US-8715698-B2 Truncated secretory aspartyl proteinase 2 PEVION BIOTECH, AG (CH) 2014-05-06 US disclosed
US-8496962-B2 Trans-adjuvant system PEVION BIOTECH, LTD. (CH) 2013-07-30 US disclosed
US-8367077-B2 Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof PEVION BIOTECH, AG (CH) 2013-02-05 US disclosed
EP-2201109-B1 TRUNCATED SECRETORY ASPARTYL PROTEINASE 2 PEVION BIOTECH LTD (CH) 2012-10-03 EP disclosed
CN-101815505-B Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof PEVION BIOTECH AG 2012-09-19 CN disclosed
US-20120195962-A1 Multiepitope Vaccine for Her2/Neu-Associated Cancers PEVION BIOTECH AG (CH) 2012-08-02 US disclosed
CN-101815505-A Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof PEVION BIOTECH AG 2010-08-25 CN disclosed
EP-2201109-A1 TRUNCATED SECRETORY ASPARTYL PROTEINASE 2 Pevion Biotech Ltd. (CH) 2010-06-30 EP disclosed
US-20100015214-A1 Novel Trans-Adjuvant System PEVION BIOTECH LTD. (CH) 2010-01-21 US disclosed
EP-2117590-A1 NON-SPECIFIC IMMUNOSTIMULATING AGENTS Pevion Biotech AG (CH) 2009-11-18 EP disclosed
WO-2009036997-A1 TRUNCATED SECRETORY ASPARTYL PROTEINASE 2 PEVION BIOTECH LTD. (CH) 2009-03-26 WO disclosed
EP-2039764-A1 Truncated secretory aspartyl proteinase 2 Pevion Biotech AG (CH) 2009-03-25 EP disclosed
EP-2014279-A1 Virosomes comprising hemagglutinin derived from an influenza virus produced in a cell line, compositions, methods of manufacturing, use thereof Pevion Biotech AG (CH) 2009-01-14 EP disclosed
WO-2008080628-A1 NON-SPECIFIC IMMUNOSTIMULATING AGENTS PEVION BIOTECH AG (CH) 2008-07-10 WO disclosed
EP-1938835-A1 Non-specific immunostimulating agents Pevion Biotech AG (CH) 2008-07-02 EP disclosed
EP-1797895-A1 An adjuvant system comprising virosomes and liposomes Pevion Biotech Ltd. (CH) 2007-06-20 EP disclosed