Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980574 | 1.00 | RAB9A (0.46) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL7764476 | 0.87 | NPC1 (0.47) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| Bromide SCHEMBL16497619 | 0.84 | KMT2A (0.45) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| Bromide SCHEMBL16497620 | 0.84 | KMT2A (0.45) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL10843581 | 0.82 | MEN1 (0.56) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL10843575 | 0.82 | MEN1 (0.56) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL29620208 | 0.81 | RAB9A (0.67) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL1898847 | 0.81 | RAB9A (0.67) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL9588524 | 0.81 | RAB9A (0.67) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| Bromide SCHEMBL8666504 | 0.80 | MEN1 (0.69) | RAB9AKMT2ANPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2318058-A2 | MEDICAL IMPLANT | AGT Sciences Limited (GB) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010007425-A2 | MEDICAL IMPLANT | AGT SCIENCES LTD (GB) | 2010-01-21 | — | — | WO | disclosed |