Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4A | O75164 | 2/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907277 | 1.00 | RAB9A (0.46) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL7764476 | 0.87 | NPC1 (0.47) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| Bromide SCHEMBL16497619 | 0.84 | KMT2A (0.45) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| Bromide SCHEMBL16497620 | 0.84 | KMT2A (0.45) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL10843581 | 0.82 | MEN1 (0.56) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL10843575 | 0.82 | MEN1 (0.56) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL29620208 | 0.81 | RAB9A (0.67) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL1898847 | 0.81 | RAB9A (0.67) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| SCHEMBL9588524 | 0.81 | RAB9A (0.67) | RAB9AKMT2ANPC1MEN1ALDH1A1 | |
| Bromide SCHEMBL8666504 | 0.80 | MEN1 (0.69) | RAB9AKMT2ANPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110218647-A1 | MEDICAL IMPLANT | AGT SCIENCES LTD. (GB) | 2011-09-08 | — | — | US | disclosed |
| US-20110152212-A1 | Aqueous Formulations | CROWTHER NICHOLAS JOHN | 2011-06-23 | — | — | US | disclosed |
| EP-2124894-A2 | AQUEOUS FORMULATIONS | AGT Sciences Limited (GB) | 2009-12-02 | — | — | EP | disclosed |
| US-20090110733-A1 | DELIVERY MEANS | AGT SCIENCES LIMITED (GB) | 2009-04-30 | — | — | US | disclosed |
| EP-1558652-B1 | DERIVATISED HYDROGELS AND THEIR USE | AGT SCIENCES LTD (GB) | 2009-02-11 | — | — | EP | disclosed |
| EP-2018191-A2 | DELIVERY MEANS | AGT Sciences Limited (GB) | 2009-01-28 | — | — | EP | disclosed |
| US-20090022781-A1 | DELIVERY MEANS | AGT SCIENCES LIMITED (GB) | 2009-01-22 | — | — | US | disclosed |
| EP-2004140-A1 | DELIVERY MEANS | AGT Sciences Limited (GB) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008102144-A2 | AQUEOUS FORMULATIONS | AGT SCIENCES LIMITED (GB) | 2008-08-28 | — | — | WO | disclosed |
| US-20070276207-A1 | Polymeric Materials Incorporating a Ph Indicator Dye | EAGLAND DONALD | 2007-11-29 | — | — | US | disclosed |
| WO-2007132244-A2 | DELIVERY MEANS | AGT SCIENCES LIMITED (GB) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007096606-A1 | DELIVERY MEANS | AGT SCIENCES LIMITED (GB) | 2007-08-30 | — | — | WO | disclosed |
| EP-1700115-A1 | POLYMERIC MATERIALS INCORPORATING A PH INDICATOR DYE | AGT Sciences Limited (GB) | 2006-09-13 | — | — | EP | disclosed |
| US-20060058459-A1 | Derivatised hydrogels and their use | UNIVERSITY OF BRADFORD | 2006-03-16 | — | — | US | disclosed |
| EP-1558652-A1 | DERIVATISED HYDROGELS AND THEIR USE | UNIVERSITY OF BRADFORD (GB) | 2005-08-03 | — | — | EP | disclosed |
| WO-2005052572-A1 | POLYMERIC MATERIALS INCORPORATING A PH INDICATOR DYE | AGT SCIENCES LIMITED (GB) | 2005-06-09 | — | — | WO | disclosed |
| WO-2004041872-A1 | DERIVATISED HYDROGELS AND THEIR USE | UNIVERSITY OF BRADFORD (GB) | 2004-05-21 | — | — | WO | disclosed |
| US-4272620-A | Polyvinyl alcohol-styrylpyridinium photosensitive resins and method for manufacture thereof | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1981-06-09 | — | — | US | disclosed |
| US-4269941-A | CONFINING THE ENZYME IN A MATRIX BY EXPOSING TO LIGHT AN AQUEOUS SOLUTION OF ENZYME AND PHOTOSENSITIVE CROSSLINKABLE RESIN COMPRISING A PARTIALLY SAPONIFIED POLYVINYL ACETATE POLYMER MODIFIED BY AN A-P-FORMYLSTYRYL/PYRIDINIUM COMPOUND | AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 1981-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090022781-A1 | DELIVERY MEANS | P4HB, GLMN, CD68 | RAB9A 3840/4885KMT2A 3492/4885NPC1 2834/4885 |
| US-20090110733-A1 | DELIVERY MEANS | LARS1, HSP90AA1, VIP | RAB9A 664/4885KMT2A 2912/4885NPC1 4267/4885 |
| US-20110152212-A1 | Aqueous Formulations | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TP53, VCL | RAB9A 1926/4885KMT2A 2530/4885NPC1 4069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.