Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12777021 | 1.00 | OPRM1 (0.41) | OPRM1SPHK1ZDHHC7LMNADNM1 | |
| SCHEMBL3312385 | 1.00 | OPRM1 (0.41) | OPRM1SPHK1ZDHHC7LMNADNM1 | |
| SCHEMBL9082555 | 1.00 | OPRM1 (0.41) | OPRM1SPHK1ZDHHC7LMNADNM1 | |
| SCHEMBL30906928 | 1.00 | OPRM1 (0.41) | OPRM1SPHK1ZDHHC7LMNADNM1 | |
| SCHEMBL10893298 | 1.00 | OPRM1 (0.41) | OPRM1SPHK1ZDHHC7LMNADNM1 | |
| SCHEMBL19532756 | 0.98 | OPRM1 (0.42) | OPRM1SPHK1ZDHHC7LMNADNM1 | |
| SCHEMBL3465318 | 0.91 | DNM1 (0.35) | OPRM1DNM1TSHR | |
| SCHEMBL398839 | 0.88 | — | — | |
| SCHEMBL397845 | 0.83 | — | — | |
| SCHEMBL20741413 | 0.81 | DNM1 (0.34) | DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499185-B1 | PROCESS FOR PREPARING CLUSTERED FUNCTIONAL POLYORGANOSILOXANES, AND METHODS FOR THEIR USE | DOW CORNING (US) | 2018-07-04 | — | — | EP | disclosed |
| US-9593209-B2 | Process for preparing clustered functional polyorganosiloxanes, and methods for their use | DOW CORNING CORPORATION (US) | 2017-03-14 | — | — | US | disclosed |
| CN-102597065-B | Process for preparing clustered functional polyorganosiloxanes, and methods for their use | DOW CORNING | 2015-07-22 | — | — | CN | disclosed |
| US-20120245272-A1 | Process for Preparing Clustered Functional Polyorganosiloxanes, and Methods for Their Use | DOW SILICONES CORPORATION | 2012-09-27 | — | — | US | disclosed |
| EP-2499185-A1 | PROCESS FOR PREPARING CLUSTERED FUNCTIONAL POLYORGANOSILOXANES, AND METHODS FOR THEIR USE | Dow Corning Corporation (US) | 2012-09-19 | — | — | EP | disclosed |
| CN-102597065-A | Process for preparing clustered functional polyorganosiloxanes, and methods for their use | DOW CORNING | 2012-07-18 | — | — | CN | disclosed |
| WO-2011056832-A1 | PROCESS FOR PREPARING CLUSTERED FUNCTIONAL POLYORGANOSILOXANES, AND METHODS FOR THEIR USE | DOW CORNING CORPORATION (US) | 2011-05-12 | — | — | WO | disclosed |