Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 1/20 | 0.31 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903889 | 0.86 | KDM4E (0.30) | — | |
| SCHEMBL1907639 | 0.86 | CYP3A4 (0.34) | — | |
| SCHEMBL1905091 | 0.84 | — | — | |
| SCHEMBL1903884 | 0.83 | AKT2 (0.33) | — | |
| SCHEMBL1905736 | 0.82 | MEN1 (0.32) | MEN1HSP90AA1KMT2A | |
| SCHEMBL1908487 | 0.81 | AKT1 (0.35) | TNK2 | |
| SCHEMBL1904285 | 0.81 | OPRL1 (0.32) | LCKTNK2 | |
| SCHEMBL1902580 | 0.79 | AKT1 (0.47) | — | |
| SCHEMBL1907804 | 0.79 | PDE2A (0.34) | MEN1HSP90AA1KMT2ALCKTNK2 | |
| SCHEMBL1905018 | 0.78 | EGFR (0.34) | LCKTNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011055115-A1 | AKT / PKB INHIBITORS | ALMAC DISCOVERY LIMITED (GB) | 2011-05-12 | — | — | WO | disclosed |