Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | GCK | P35557 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3592344 | 0.85 | SMN1; SMN2 (0.62) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL3599480 | 0.84 | MEN1 (0.79) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL13441597 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL3586824 | 0.82 | SPHK2 (0.58) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL14506210 | 0.82 | SPHK2 (0.55) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL13702365 | 0.82 | SMPD1 (0.76) | HTTSRD5A2RAB9AMRGPRX4KMT2A | |
| SCHEMBL3601138 | 0.82 | SRD5A2 (0.62) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL14533430 | 0.82 | PARP10 (0.63) | ALDH1A1HTTSMN1; SMN2L3MBTL1SRD5A2 | |
| SCHEMBL1056460 | 0.80 | MRGPRX4 (0.74) | ALDH1A1SMN1; SMN2L3MBTL1SRD5A2MAPT | |
| SCHEMBL17414619 | 0.78 | MAOB (0.55) | ALDH1A1HTTSMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141385-B1 | TARGET MOLECULE ATTACHMENT TO SURFACES | SURMODICS INC (US) | 2017-07-05 | — | — | EP | disclosed |