Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL391547 | 0.90 | MEN1 (0.71) | SMN1; SMN2KMT2AMAPTRAB9ALMNA | |
| SCHEMBL14166298 | 0.89 | SRD5A2 (0.71) | SMN1; SMN2ALDH1A1HTTL3MBTL1KMT2A | |
| SCHEMBL183994 | 0.87 | LMNA (0.70) | SMN1; SMN2KMT2AMAPTRAB9ASRD5A2 | |
| SCHEMBL29788280 | 0.86 | LMNA (0.65) | SMN1; SMN2KMT2ARAB9AGAALMNA | |
| SCHEMBL340311 | 0.86 | LMNA (0.65) | SMN1; SMN2KMT2ARAB9AGAALMNA | |
| SCHEMBL3599480 | 0.85 | MEN1 (0.79) | SMN1; SMN2ALDH1A1HTTL3MBTL1KMT2A | |
| SCHEMBL19074331 | 0.85 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1HTTL3MBTL1KMT2A | |
| SCHEMBL8900334 | 0.84 | SMPD1 (0.60) | SMN1; SMN2KMT2AMAPTRAB9ALMNA | |
| SCHEMBL6664749 | 0.84 | LMNA (0.63) | SMN1; SMN2ALDH1A1HTTL3MBTL1KMT2A | |
| SCHEMBL3129603 | 0.83 | MEN1 (0.74) | SMN1; SMN2KMT2ARAB9ASRD5A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1141385-B1 | TARGET MOLECULE ATTACHMENT TO SURFACES | SURMODICS INC (US) | 2017-07-05 | — | — | EP | disclosed |
| US-7691787-B2 | Target molecule attachment to surfaces | SURMODICS, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-20070104757-A1 | LATENT REACTIVE BLOOD COMPATIBLE AGENTS | Surmodics Coatings, LLC | 2007-05-10 | — | — | US | disclosed |
| US-20070082022-A1 | LATENT REACTIVE BLOOD COMPATIBLE AGENTS | Surmodics Coatings, LLC | 2007-04-12 | — | — | US | disclosed |
| US-7144573-B2 | Latent reactive blood compatible agents | SURMODICS, INC. (US) | 2006-12-05 | — | — | US | disclosed |
| US-7071235-B2 | Latent reactive blood compatible agents | SURMODICS, INC. (US) | 2006-07-04 | — | — | US | disclosed |
| EP-1069916-B1 | LATENT REACTIVE BLOOD COMPATIBLE AGENTS | SURMODICS INC (US) | 2006-05-10 | — | — | EP | disclosed |
| US-20060052460-A1 | Latent reactive blood compatible agents | Surmodics Coatings, LLC | 2006-03-09 | — | — | US | disclosed |
| US-20050170427-A1 | Target molecule attachment to surfaces | SURMODICS, INC. (US) | 2005-08-04 | — | — | US | disclosed |
| EP-1019424-B1 | REAGENT AND METHOD FOR ATTACHING TARGET MOLECULES TO A SURFACE | SURMODICS INC (US) | 2005-01-12 | — | — | EP | disclosed |
| EP-0888389-A4 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SURMODICS INC (US) | 2001-03-14 | — | — | EP | disclosed |
| EP-1069916-A2 | LATENT REACTIVE BLOOD COMPATIBLE AGENTS | SurModics, Inc. (US) | 2001-01-24 | — | — | EP | disclosed |
| EP-1019424-A2 | REAGENT AND METHOD FOR ATTACHING TARGET MOLECULES TO A SURFACE | SurModics, Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-2000040593-A2 | TARGET MOLECULE ATTACHMENT TO SURFACES | SURMODICS, INC. (US) | 2000-07-13 | — | — | WO | disclosed |
| WO-1999047176-A2 | LATENT REACTIVE BLOOD COMPATIBLE AGENTS | SURMODICS, INC. (US) | 1999-09-23 | — | — | WO | disclosed |
| US-5942555-A | Photoactivatable chain transfer agents and semi-telechelic photoactivatable polymers prepared therefrom | SURMODICS, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1999016907-A2 | REAGENT AND METHOD FOR ATTACHING TARGET MOLECULES TO A SURFACE | SURMODICS, INC. (US) | 1999-04-08 | — | — | WO | disclosed |
| US-5858653-A | Reagent and method for attaching target molecules to a surface | SURMODICS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| EP-0888389-A1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | SurModics, Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997034935-A1 | PHOTOACTIVATABLE CHAIN TRANSFER AGENTS | BSI CORPORATION (US) | 1997-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052460-A1 | Latent reactive blood compatible agents | FGB, HLA-A, HLA-C | SMN1; SMN2 4383/4885ALDH1A1 530/4885HTT 3760/4885 |
| US-20050170427-A1 | Target molecule attachment to surfaces | EPCAM, PCNA, POLM | SMN1; SMN2 4589/4885ALDH1A1 1754/4885HTT 4523/4885 |
| US-20070082022-A1 | LATENT REACTIVE BLOOD COMPATIBLE AGENTS | FGB, HLA-A, HLA-C | SMN1; SMN2 4383/4885ALDH1A1 530/4885HTT 3760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.