Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Xylitol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribitol SCHEMBL4316278 | 1.00 | LMNA (0.67) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Xylitol SCHEMBL5836739 | 1.00 | LMNA (0.67) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Adonitol SCHEMBL27551573 | 1.00 | LMNA (0.67) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Xylitol SCHEMBL19180061 | 1.00 | LMNA (0.67) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Galactitol SCHEMBL9686277 | 0.97 | LMNA (0.73) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL31107070 | 0.93 | LMNA (0.79) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Sorbitol SCHEMBL1079506 | 0.93 | LMNA (0.79) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL76098 | 0.93 | LMNA (0.79) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL28035901 | 0.93 | LMNA (0.79) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| Mannitol SCHEMBL2489294 | 0.93 | LMNA (0.79) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-209669095-U | Integrated evaporation, crystallization and centrifuge separation prepare the device of xylitol | ZHEJIANG HUAKANG PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | claimed |
| CN-109761755-A | Integrated evaporation, crystallization and centrifuge separation prepare the device and control method of xylitol | 浙江华康药业股份有限公司 | 2019-05-17 | — | — | CN | claimed |
| CN-104706858-A | Oral cavity health spray and preparation method thereof | LIU BO | 2015-06-17 | — | — | CN | claimed |
| EP-1044168-B1 | POLYLACTATE RELEASE COMPOUNDS AND METHODS OF USING SAME | REGENESIS BIOREMEDIATION PRODU (US) | 2003-08-27 | — | — | EP | claimed |
| EP-0856515-B1 | Method of making acetals | MILLIKEN & CO (US) | 2001-12-05 | — | — | EP | claimed |
| EP-0918057-B1 | Carbamoyl substituted acetals and compositions containing the same | MILLIKEN RES CORP (US) | 2001-09-12 | — | — | EP | claimed |
| US-20250163362-A1 | RECOMBINANT YEASTS WITH RECOMBINANT XYLOSE REDUCTASE, XYLITOL DEHYDROGENASE, AND/OR XYLULOKINASE GENES AND METHODS OF USING SAME | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2025-05-22 | — | — | US | disclosed |
| WO-2024151647-A2 | POLYOL SWEETENERS AND CARDIOVASCULAR AND THROMBOTIC EVENT RISK | THE CLEVELAND CLINIC FOUNDATION (US) | 2024-07-18 | — | — | WO | disclosed |
| EP-3229792-B1 | COMPOSITION FOR THE RELIEF OF DRY MOUTH | ELEVATE ORAL CARE LLC (US) | 2024-02-07 | — | — | EP | disclosed |
| EP-4313907-A1 | REFRACTORY BINDER | Bugajski, Jerzy (AT) | 2024-02-07 | — | — | EP | disclosed |
| CN-116616396-A | Preparation method of natural solid beverage and bubble water thereof | 深圳安吉尔饮水产业集团有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116422147-A | Anticoagulation hemodialysis membrane, and preparation method and application thereof | 杨婷婷 | 2023-07-14 | — | — | CN | disclosed |
| EP-4149428-A1 | COMBINED HYPEROSMOLAR SOLUTION FOR INFUSION | M.T.K. Medical Center Limited Liability Company (UA) | 2023-03-22 | — | — | EP | disclosed |
| WO-1992006943-A1 | LIQUID XYLITOL | XYROFIN OY (FI) | 1992-04-30 | — | — | WO | disclosed |
| US-5081026-A | Fermentation of Xylose Solution with Yeast | SUOMEN XYROFIN OY (FI) | 1992-01-14 | — | — | US | disclosed |
| EP-0454702-A1 | METHOD FOR THE PRODUCTION OF XYLITOL FROM MIXTURES CONTAINING XYLOSE. | XYROFIN OY (FI) | 1991-11-06 | — | — | EP | disclosed |
| WO-1991015963-A1 | SHORTENING COMPOSITIONS CONTAINING POLYOL FATTY ACID POLYESTERS | THE PROCTER & GAMBLE COMPANY (US) | 1991-10-31 | — | — | WO | disclosed |
| WO-1991015960-A1 | NOVEL SOLID, NONDIGESTIBLE, FAT-LIKE COMPOUNDS AND FOOD COMPOSITIONS CONTAINING SAME | THE PROCTER & GAMBLE COMPANY (US) | 1991-10-31 | — | — | WO | disclosed |
| WO-1991015961-A1 | REDUCED CALORIE POURABLE SHORTENINGS, COOKING OILS, SALAD OILS OR LIKE COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1991-10-31 | — | — | WO | disclosed |
| WO-1990008193-A1 | METHOD FOR THE PRODUCTION OF XYLITOL FROM MIXTURES CONTAINING XYLOSE | SUOMEN XYROFIN OY (FI) | 1990-07-26 | — | — | WO | disclosed |