Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 4/20 | 0.41 |
| ▸ | MC5R | P33032 | 4/20 | 0.41 |
| ▸ | MC3R | P41968 | 4/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 3/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1903784 | 1.00 | MEN1 (0.47) | MEN1KMT2AMC4RMC5RMC3R | |
| SCHEMBL1901984 | 0.92 | MEN1 (0.39) | MEN1KMT2AALDH1A1TACR1 | |
| SCHEMBL1905042 | 0.92 | MEN1 (0.39) | MEN1KMT2APOLBALDH1A1TACR1 | |
| SCHEMBL1902249 | 0.92 | MEN1 (0.39) | MEN1KMT2APOLBALDH1A1TACR1 | |
| SCHEMBL1904624 | 0.92 | MEN1 (0.39) | MEN1KMT2APOLBALDH1A1TACR1 | |
| SCHEMBL1904713 | 0.92 | LCK (0.39) | MEN1KMT2ATACR1 | |
| SCHEMBL1906321 | 0.90 | KMT2A (0.41) | MEN1KMT2AAADATPOLBALDH1A1 | |
| SCHEMBL1908228 | 0.90 | KMT2A (0.41) | MEN1KMT2AAADATPOLBALDH1A1 | |
| SCHEMBL1902540 | 0.89 | MEN1 (0.38) | MEN1KMT2AMC4RMC5RMC3R | |
| SCHEMBL1907208 | 0.89 | MEN1 (0.38) | MEN1KMT2AMC4RMC5RMC3R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051673-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS KLK1 INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |
| WO-2011051673-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS KLK1 INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | disclosed |