Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908228 | 1.00 | KMT2A (0.41) | KMT2ACCNT1MEN1AADATTACR1 | |
| SCHEMBL1906919 | 0.91 | CTSB (0.40) | AADATALDH1A1CTSSCTSKCTSV | |
| SCHEMBL1906106 | 0.91 | CTSL (0.47) | CTSSCTSKCTSVCTSL | |
| SCHEMBL1905802 | 0.91 | CTSL (0.47) | CTSSCTSKCTSVCTSL | |
| SCHEMBL1905042 | 0.90 | MEN1 (0.39) | KMT2AMEN1TACR1ALDH1A1LMNA | |
| SCHEMBL1904624 | 0.90 | MEN1 (0.39) | KMT2AMEN1TACR1ALDH1A1LMNA | |
| SCHEMBL1902249 | 0.90 | MEN1 (0.39) | KMT2AMEN1TACR1ALDH1A1LMNA | |
| SCHEMBL1907660 | 0.90 | MEN1 (0.47) | KMT2AMEN1AADATTACR1ALDH1A1 | |
| SCHEMBL1903784 | 0.90 | MEN1 (0.47) | KMT2AMEN1AADATTACR1ALDH1A1 | |
| SCHEMBL1907208 | 0.88 | MEN1 (0.38) | KMT2AMEN1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011051673-A1 | AMINOTHIAZOLE DERIVATIVES USEFUL AS KLK1 INHIBITORS | VANTIA LIMITED (GB) | 2011-05-05 | — | — | WO | claimed |