Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.76 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.76 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.60 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MDH1 | P40925 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19078986 | 0.98 | CYP4A11 (0.78) | CYP4A11CYP4F2LOXL2SLC7A5DHODH | |
| SCHEMBL6614812 | 0.95 | CYP4A11 (0.73) | CYP4A11CYP4F2LOXL2SLC7A5DHODH | |
| SCHEMBL244703 | 0.89 | CYP4F2 (0.73) | CYP4A11CYP4F2LOXL2SLC7A5FOLH1 | |
| SCHEMBL26239703 | 0.88 | CYP4F2 (0.76) | CYP4A11CYP4F2LOXL2SLC7A5MDH1 | |
| SCHEMBL15174613 | 0.88 | CYP4F2 (0.76) | CYP4A11CYP4F2LOXL2SLC7A5MDH1 | |
| SCHEMBL15174508 | 0.88 | CYP4F2 (0.76) | CYP4A11CYP4F2LOXL2SLC7A5MDH1 | |
| SCHEMBL31752933 | 0.88 | CYP4A11 (0.97) | CYP4A11CYP4F2LOXL2SLC7A5DHODH | |
| SCHEMBL19889923 | 0.87 | CYP4F2 (0.74) | CYP4A11CYP4F2LOXL2SLC7A5DHODH | |
| SCHEMBL18540811 | 0.86 | CYP4A11 (1.00) | CYP4A11CYP4F2LOXL2SLC7A5DHODH | |
| SCHEMBL70173 | 0.85 | CYP4F2 (0.83) | CYP4A11CYP4F2LOXL2SLC7A5DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3397614-B1 | IONIZABLE CATIONIC LIPID | ARCTURUS THERAPEUTICS INC (US) | 2022-05-18 | — | — | EP | disclosed |
| WO-2017117530-A9 | IONIZABLE CATIONIC LIPID | ARCTURUS THERAPEUTICS, INC. (US) | 2021-03-11 | — | — | WO | disclosed |
| US-20180050987-A1 | AROMATIC IONIZABLE CATIONIC LIPID | ARCTURUS THERAPEUTICS, INC. | 2018-02-22 | — | — | US | disclosed |
| US-9834510-B2 | Aromatic ionizable cationic lipid | ARCTURUS THERAPEUTICS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| US-9834510-B2 | Aromatic ionizable cationic lipid | ARCTURUS THERAPEUTICS, INC. (US) | 2017-12-05 | — | — | US | disclosed |
| WO-2017117530-A1 | IONIZABLE CATIONIC LIPID | ARCTURUS THERAPEUTICS, INC. (US) | 2017-07-06 | — | — | WO | disclosed |
| US-20170190661-A1 | Aromatic Ionizable Cationic Lipid | ARCTURUS THERAPEUTICS, INC. | 2017-07-06 | — | — | US | disclosed |
| US-20170190661-A1 | Aromatic Ionizable Cationic Lipid | ARCTURUS THERAPEUTICS, INC. | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180050987-A1 | AROMATIC IONIZABLE CATIONIC LIPID | SGMS1, SLCO4C1, SLCO2B1 | CYP4A11 433/4885CYP4F2 643/4885LOXL2 427/4885 |
| US-20170190661-A1 | Aromatic Ionizable Cationic Lipid | SGMS1, SLC7A1, SLCO2B1 | CYP4A11 476/4885CYP4F2 494/4885LOXL2 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.