Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 5/20 | 0.73 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.73 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.62 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19078986 | 0.97 | CYP4A11 (0.78) | CYP4A11CYP4F2LOXL2SLC7A5MRGPRX4 | |
| SCHEMBL19078992 | 0.95 | CYP4A11 (0.76) | CYP4A11CYP4F2LOXL2SLC7A5MRGPRX4 | |
| SCHEMBL244703 | 0.90 | CYP4F2 (0.73) | CYP4A11CYP4F2LOXL2SLC7A5MRGPRX4 | |
| SCHEMBL70173 | 0.87 | CYP4F2 (0.83) | CYP4A11CYP4F2LOXL2SLC7A5MRGPRX4 | |
| SCHEMBL1792728 | 0.86 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2SLC7A5MRGPRX4 | |
| SCHEMBL10606812 | 0.86 | CYP4A11 (0.75) | CYP4A11CYP4F2LOXL2SLC7A5MRGPRX4 | |
| SCHEMBL5663990 | 0.86 | CYP4A11 (0.91) | CYP4A11CYP4F2LOXL2SLC7A5MRGPRX4 | |
| SCHEMBL18540809 | 0.85 | CYP4A11 (0.66) | CYP4A11CYP4F2LOXL2SLC7A5MRGPRX4 | |
| SCHEMBL17563119 | 0.85 | CYP4F2 (0.76) | CYP4A11CYP4F2ALDH1A1HPGDMAPT | |
| SCHEMBL8921794 | 0.84 | CYP4A11 (0.73) | CYP4A11CYP4F2LOXL2SLC7A5MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321425-B | Synthesis method of 4- (3-bromopropyl) methyl benzoate | 上海毕得医药科技股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-112321425-A | Synthesis method of 4- (3-bromopropyl) methyl benzoate | 上海毕得医药科技股份有限公司 | 2021-02-05 | — | — | CN | disclosed |
| EP-0683781-B1 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE | METABASIS THERAPEUTICS INC (US) | 2004-04-21 | — | — | EP | disclosed |
| US-5731432-A | Inhibitors of adenosine monophosphate deaminase | GENSIA SICOR INC. (US) | 1998-03-24 | — | — | US | disclosed |
| EP-0683781-A4 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE. | GENSIA PHARMA (US) | 1997-05-28 | — | — | EP | disclosed |
| EP-0683781-A1 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE | GENSIA PHARMACEUTICALS, INC. (US) | 1995-11-29 | — | — | EP | disclosed |
| WO-1994018200-A1 | NOVEL INHIBITORS OF ADENOSINE MONOPHOSPHATE DEAMINASE | GENSIA, INC. (US) | 1994-08-18 | — | — | WO | disclosed |