SCHEMBL19081722

SCHEMBL19081722

c1ccc2c(c1)ccc1c3cc4oc5ccccc5c4c(-c4c5ccccc5c(-c5ccc6sc7ccccc7c6c5)c5ccccc45)c3oc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
CYP1A1 P04798 10/20 0.32
CYP1B1 Q16678 10/20 0.32
ABCB1 P08183 3/20 0.32
ABCC1 P33527 3/20 0.32
ABCG2 Q9UNQ0 3/20 0.32
CYP1A2 P05177 9/20 0.31
PRKDC P78527 2/20 0.31
PSMD14 O00487 1/20 0.31
CSNK2A2 P19784 1/20 0.31
CSNK2B P67870 1/20 0.31
CSNK2A1 P68400 1/20 0.31
XDH P47989 1/20 0.31
KDM4E B2RXH2 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
ALOX15 P16050 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17944911 0.88 ESR2 (0.36) KDM4EALDH1A1HPGDMAPTKMT2A
SCHEMBL19081473 0.86 CYP1A1 (0.44) TDP1L3MBTL1CYP1A1CYP1B1ABCB1
SCHEMBL16067771 0.84 CYP1A1 (0.38) TDP1L3MBTL1CYP1A1CYP1B1ABCB1
SCHEMBL19081714 0.83 CYP1A1 (0.36) TDP1CYP1A1CYP1B1ABCB1ABCC1
SCHEMBL17931989 0.81 CYP1A1 (0.38) TDP1CYP1A1CYP1B1ABCB1ABCC1
SCHEMBL19081710 0.81 CYP1A1 (0.36) TDP1L3MBTL1CYP1A1CYP1B1ABCB1
SCHEMBL19081724 0.80 CYP1A1 (0.34) TDP1L3MBTL1CYP1A1CYP1B1ABCB1
SCHEMBL23427978 0.80 CYP1A1 (0.37) TDP1L3MBTL1CYP1A1CYP1B1ABCB1
SCHEMBL19076598 0.80 TDP1 (0.33) TDP1L3MBTL1ALDH1A1HPGDMAPT
SCHEMBL19109921 0.80 ESR2 (0.32) TDP1L3MBTL1CYP1A2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-04 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10553800-B2 Condensed cyclic compound and an organic light-emitting device including the same CRY1, CRY2, CCNT1 TDP1 2322/4885L3MBTL1 1245/4885CYP1A1 184/4885
US-20170194572-A1 CONDENSED CYCLIC COMPOUND AND AN ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNT1 TDP1 2322/4885L3MBTL1 1245/4885CYP1A1 184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.